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(7-chloroquinolin-4-yl)hydrazine

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Identification
Molecular formula
C9H8ClN3
CAS number
637-27-0
IUPAC name
(7-chloro-4-quinolyl)hydrazine
State
State

At room temperature, this compound is typically a solid.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
525.70
Boiling point (Kelvin)
798.80
General information
Molecular weight
179.63g/mol
Molar mass
179.6160g/mol
Density
1.3900g/cm3
Appearence

(7-chloroquinolin-4-yl)hydrazine typically appears as an off-white to light brown powder.

Comment on solubility

Solubility of (7-chloro-4-quinolyl)hydrazine

(7-chloro-4-quinolyl)hydrazine is a compound that exhibits specific solubility characteristics that may be important for its application in various fields. Here are some key points regarding its solubility:

  • Polarity: The presence of both a quinoline structure and a hydrazine group suggests a degree of polarity, which can affect solubility in different solvents.
  • Solvent Compatibility: This compound is likely soluble in polar organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), while demonstrating lower solubility in apolar solvents like hexane.
  • Hydrogen Bonding: The hydrazine group can engage in hydrogen bonding, enhancing its solubility in polar solvents and making it more interactive with other polar molecules.
  • pH Influence: The solubility of (7-chloro-4-quinolyl)hydrazine may also be affected by the pH of the solvent, as acidic or basic conditions could influence its overall charge and, consequently, its solubility.

In conclusion, understanding the solubility profile of (7-chloro-4-quinolyl)hydrazine is crucial for its effective application and handling. As with many organic compounds, exploring various solvent interactions can yield valuable insights into its practical uses in chemical synthesis and medicinal chemistry.

Interesting facts

Introduction to (7-chloro-4-quinolyl)hydrazine

(7-chloro-4-quinolyl)hydrazine is a fascinating compound that belongs to the class of hydrazines, which are known for their diverse applications in medicinal chemistry and agrochemicals. This compound, with a unique structure, combines the quinoline ring system with a hydrazine moiety, opening the door to a variety of properties and uses.

Interesting Facts

  • Pharmaceutical Relevance: Compounds containing quinoline derivatives are often reported to exhibit significant biological activities, including antimicrobial, antimalarial, and anticancer properties. This makes (7-chloro-4-quinolyl)hydrazine of great interest in drug discovery.
  • Potential Mechanisms: The hydrazine functionality can participate in hydrogen bonding and may influence the compound's interaction with biological targets. This aspect makes it a subject of research for understanding its mechanism of action in therapeutic applications.
  • Research Applications: Scientists are continuously investigating the potential of (7-chloro-4-quinolyl)hydrazine in various setups, including its role as a ligand in coordination chemistry and its synthetic utility in creating novel compounds with enhanced properties.
  • Environmental Considerations: While exploring hydrazines, it is essential to address their environmental implications. Some hydrazine derivatives can be toxic, hence studies focus on safer alternatives and methods of remediation.
  • Intriguing Structure: The incorporation of chlorine in the quinoline ring significantly alters the electronic properties of the molecule, affecting its solubility and reactivity, which are crucial aspects for chemists to consider during synthesis and application.

The investigation of (7-chloro-4-quinolyl)hydrazine opens up exciting pathways in both synthesis and application. Ongoing research continues to unveil its potential, highlighting the importance of innovative compounds in the field of chemistry and pharmaceuticals.

Synonyms
23834-14-2
7-chloro-4-hydrazinylquinoline
RefChem:546180
628-226-0
7-Chloro-4-hydrazinoquinoline
(7-chloroquinolin-4-yl)hydrazine
QUINOLINE, 7-CHLORO-4-HYDRAZINO-
MFCD00006776
4-Hydrazino-7-chloroquinoline
(7-chloro-4-quinolyl)hydrazine
7-chloro-4-quinolylhydrazine
BRN 0141468
7-Chloro-4-hydrazino-quinoline
1-(7-chloro-4-quinolyl)hydrazine
NSC10802
4-22-00-07045 (Beilstein Handbook Reference)
SCHEMBL2455864
7-chloroquinolin-4-yl-hydrazine
CHEMBL3423374
SCHEMBL30028448
DTXSID80178539
HMS1786E14
(7-chloro-quinolin-4-yl)-hydrazine
AB8882
BBL027609
NSC 10802
NSC-10802
SBB000320
STL163512
7-Chloro-4-hydrazinoquinoline, 98%
AKOS000119445
SB67548
SY261053
DB-046260
ST51006947
EN300-17253
3E-912
Z56899192