Interesting facts
Interesting Facts about 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
This compound, commonly categorized as a benzodiazepine derivative, has attracted the attention of many researchers due to its unique chemical properties and activities. Here are some notable points regarding this intriguing molecule:
- Pharmacological Potential: Compounds in the benzodiazepine class are recognized for their ability to enhance the effect of the neurotransmitter GABA. This leads to sedative, anxiolytic, anticonvulsant, and muscle relaxant effects, making it a significant area of research in psychopharmacology.
- Substituent Effects: The presence of chlorine atoms at specific positions, such as the 2-position on the phenyl ring and the 7-position on the benzodiazepine core, can influence the compound’s biological activity, potency, and pharmacokinetics. This highlights the importance of studying structure-activity relationships within the benzodiazepine family.
- Drug Development: The exploration of derivatives like this compound shows promise in developing new therapeutic agents that may have reduced side effects or improved efficacy compared to traditional benzodiazepines. This compound could contribute to ongoing efforts to refine treatments for anxiety and sleep disorders.
- Research Applications: Given its structural complexity, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one serves as a valuable subject in medicinal chemistry, especially for researchers aiming to synthesize analogues for testing biological effects.
Furthermore, the study of benzodiazepines like this compound is pivotal in addressing challenges such as drug tolerance and dependence, which are central to the dialogue on safe mental health treatments.
As Professor X once noted, "The intricacies of molecular modifications can lead to breakthroughs in pharmacotherapy, emphasizing the art of chemistry as both a science and a craft."
In conclusion, the ongoing exploration of compounds like 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one enriches our understanding of chemical behavior and therapeutic potential, paving the way for future advancements in the field.
Synonyms
Delorazepam
2894-67-9
Chlordemethyldiazepam
B1, Benzodiazepine
Delorazepam [INN]
Cl-DMDZ
Clordesmetildiazepam
2-Chloronordiazepam
2'-chloronordiazepam
Delorazepamum
Dadumir
EN [Anticonvulsant]
Ro 5-3027
Delorazepamum [INN-Latin]
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
Clordesmetildiazepam [Spanish]
NSC 169895
RV-12165
7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
EINECS 220-771-9
Dadumir (TN)
Delorazepam (INN)
NSC-169895
BRN 0754062
O91W32476G
1,3-Dihydro-7-chloro-5-(o-chlorophenyl)-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
DELORAZEPAM [MART.]
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-
DELORAZEPAM [WHO-DD]
DTXSID70183137
5-24-04-00331 (Beilstein Handbook Reference)
2H-1,4-BENZODIAZEPIN-2-ONE, 1,3-DIHYDRO-7-CHLORO-5-(2-CHLOROPHENYL)-
NSC169895
EN (Anticonvulsant)
chlorodesmethyldiazepam
Delorazepamum (INN-Latin)
DELORAZEPAM (MART.)
Delorazepam EG
Delorazepam DOC
Delorazepam Teva
Delorazepam Almus
Delorazepam Alter
Delorazepam Hexal
Delorazepam Mylan
Delorazepam Pensa
Delorazepam Germed
Delorazepam Sandoz
Delorazepam Ranbaxy
Delorazepam Winthrop
Delorazepam Aurobindo
Delorazepam ratiopharm
7-chloro-5-(2-chlorophenyl) 1,3-dihydro-2H-1,4-benzodiazepin-2-one
DTXCID80105628
7-chloro-5-(2-chlorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-(9CI)
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-(8CI)
220-771-9
chlordesmethyldiazepam
7-chloro-5-(2-chloro-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CHEMBL268254
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Delorazepam (100 ug/mL in Methanol)
DEA No. 2754
UNII-O91W32476G
Cambridge id 6782587
Oprea1_689003
SCHEMBL157332
O-CHLORODESMETHYLDIAZEPAM
CHEBI:135295
Delorazepam 0.1 mg/ml in Methanol
Delorazepam, 1mg/ml in Acetonitrile
BDBM50026858
STK072416
STL149558
AKOS002312613
AKOS005749640
DB01511
WLN: T67 GMV JN IHJ CG KR BG
AC-15739
DB-008912
NS00004525
D07784
AB00119043-01
SR-01000243030
2H-1, 1,3-dihydro-7-chloro-5-(2-chlorophenyl)-
2H-1, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-
2H-1, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-
Q3705147
SR-01000243030-1
7-chloro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2-ol
7-chloro-5-(2-chlorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one
1,3-dihydro-7-chloro-5-(2-chlorophenyl)-2H-1,4-benzodiazepin-2-one
7-chloro-5-(2'-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chloro-phenyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one
Solubility of 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
The solubility characteristics of 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one are important for its application in pharmaceuticals and chemical industries. Understanding its solubility can provide insights into its bioavailability and efficacy in biological systems.
Key Points on Solubility:
In conclusion, while specific solubility data may vary, it is essential to explore the conditions that maximize the solubility of 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one for optimal performance in targeted applications. Understanding these factors is crucial for enhancing its utility in medicinal chemistry.