Interesting facts
Interesting Facts about 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
The compound 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one belongs to the benzodiazepine class, which is widely recognized for its psychoactive properties. Here are some intriguing facets regarding this compound:
- Benzodiazepine Class: This compound shares its structural features with other benzodiazepines, which are known to exert anxiolytic, sedative, and muscle relaxant effects.
- Clarity in Chemistry: The presence of chlorine substituents in its structure plays a crucial role in modifying the pharmacological activity and potency of the compound.
- Mechanism of Action: Like many benzodiazepines, it is believed to enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA), which contributes to its calming effects.
- Applications: Compounds in this category are frequently utilized in the treatment of anxiety disorders, insomnia, and seizures, showcasing their significance in medicinal chemistry.
- Research Potential: The specific modifications to its structure offer a fascinating avenue for ongoing research aimed at developing newer anxiolytic drugs with fewer side effects.
As a scientist or a chemistry student, understanding this compound not only enhances knowledge of pharmacology but also highlights the intricate relationship between chemical structure and biological activity. Furthermore, the explorations of such compounds can lead to advancements in therapeutic agents, emphasizing the significance of continual research in medicinal chemistry.
Synonyms
Lormetazepam
Methyllorazepam
N-Methyllorazepam
Loramet
Noctamid
848-75-9
Lormetazepamum
Chlorotemazepam
Ergocalm
Noctamide
Loramet (TN)
WY-4082
Ro 5-5516
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
Lormetazepamum [INN-Latin]
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
Dormagen
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Lormetazepam [USAN:INN:BAN:JAN]
()-Lorazepam
EINECS 212-700-5
BRN 0759821
GU56C842ZA
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-
CHEBI:52993
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
LORMETAZEPAM [MI]
LORMETAZEPAM [INN]
LORMETAZEPAM [JAN]
LORMETAZEPAM [USAN]
LORMETAZEPAM [MART.]
LORMETAZEPAM [WHO-DD]
2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-
DTXSID40862442
Lormetazepamum (INN-Latin)
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
LORMETAZEPAM (MART.)
7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
DTXCID10811205
N05CD06
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-1h-1,4-benzodiazepin-2(3h)-one
212-700-5
(+-)-lormetazepam
WY 4082
CHEMBL22097
Lormetazepam (1.0mg/ml in Acetonitrile)
(RS)-Lormetazepam
(+/-)-Lormetazepam
UNII-GU56C842ZA
Loretam
DEA No. 2774
(+-)-Lorazepam
SCHEMBL43267
GTPL7553
Lormetazepam (JAN/USAN/INN)
Lormetazepam 0.1 mg/ml in Methanol
Lormetazepam 1.0 mg/ml in Methanol
Lormetazepam, 1mg/ml in Acetonitrile
DB13872
FL24939
ZK-65997
NS00010067
D01657
Q186257
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one #
Solubility of 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
The solubility of 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one is an important factor in its pharmacokinetics and applications. Understanding how this compound behaves in different solvent environments allows researchers and pharmacists to optimize its usage. Here’s an overview of its solubility characteristics:
In summary, the solubility of 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one is influenced by various factors, notably polarity, pH, and temperature, which can be critical for ensuring effective delivery in medicinal use.