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Diazepam

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Identification
Molecular formula
C16H13ClN2O
CAS number
439-14-5
IUPAC name
7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one
State
State

Diazepam is typically found as a solid at room temperature.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
389.00
Boiling point (Kelvin)
662.15
General information
Molecular weight
284.75g/mol
Molar mass
284.7540g/mol
Density
1.3040g/cm3
Appearence

Diazepam usually appears as a white to light yellow crystalline powder. It is often sold in tablet form, which can be any of a variety of colours, depending on the manufacturer. The compound is tasteless and odourless.

Comment on solubility

Solubility of 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one

The solubility of the compound 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one is of significant interest due to its complex structure and potential applications. Understanding its solubility can provide insights into its behavior in various environments. Here are several key points to consider:

  • Solvent Interaction: This compound may exhibit varying solubility in polar and non-polar solvents, influenced by its functional groups and ring structures.
  • Polarity: The presence of chlorine and the methyl group can affect the overall polarity, often leading to increased solubility in organic solvents while being less soluble in water.
  • pH Dependence: The solubility may change with pH, particularly if the compound can ionize or if it forms salts.
  • Temperature Effects: Like many organic compounds, increased temperature typically enhances solubility, this Compound may behave similarly.

It is essential to note that the solubility is not just a physical property but greatly impacts the compound's bioavailability and reactivity in different chemical processes. In conclusion, exploring the solubility characteristics of 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one can lead to better understanding and utilization in pharmaceutical and chemical applications.

Interesting facts

Interesting Facts about 7-Chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one

This compound is a fascinating member of the benzodiazepine family, which is renowned for its sedative and anxiolytic properties. One standout characteristic of benzodiazepines is their ability to modulate the gamma-aminobutyric acid (GABA) neuroreceptors, leading to increased inhibitory neurotransmission. This compound, in particular, presents several noteworthy aspects:

  • Structural Diversity: The presence of a cyclohexen-1-yl group introduces unique structural features that can affect the compound’s biological activity and pharmacokinetic properties.
  • Pharmacological Potential: Research into similar benzodiazepines suggests potential applications in treating anxiety, sleep disorders, and certain neurological conditions.
  • Research Interests: Scientists are continually exploring new synthetic routes to develop analogs that can provide a better therapeutic profile with fewer side effects.
  • Significance in Medicinal Chemistry: This compound serves as a model for the exploration of structure-activity relationships (SAR), allowing researchers to understand how modifications can impact efficacy and safety.

As a member of a class of compounds often prescribed in clinical settings, the importance of studying derivatives like 7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one cannot be overstated. The quest for more effective and safer medications drives ongoing research in this area, providing exciting opportunities for discovery and advancement in medicinal chemistry.

In the words of a prominent chemist, "The beauty of chemistry lies not only in its complexity but in its profound ability to impact human health." This compound is a prime example of this philosophy.

Synonyms
Tetrazepam
Myolastan
Musaril
Clinoxan
CB 4261
Tetrazepamum
Tetrazepamum [INN-Latin]
Ro 06-6657
4261 CB
EINECS 233-837-7
Myolastan (TN)
Tetrazepam (INN)
Tetrazepam [INN:BAN:DCF]
UNII-FO92091VP8
BRN 0890548
FO92091VP8
TETRAZEPAM [MI]
7-Chloro-5-(cyclohexen-1-yl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
TETRAZEPAM [INN]
2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-5-(1-CYCLOHEXEN-1-YL)-1,3-DIHYDRO-1-METHYL-
TETRAZEPAM [MART.]
CB-4261
TETRAZEPAM [WHO-DD]
7-Chloro-5-(1-cyclohexenyl)-1-methyl-2-oxo-2,3-dihydro-1H-(1,4)-benzo(f)diazepine
TETRAZEPAM [EP MONOGRAPH]
DTXSID00146058
5-24-04-00064 (Beilstein Handbook Reference)
Tetrazepamum (INN-Latin)
TETRAZEPAM (MART.)
TETRAZEPAM (EP MONOGRAPH)
7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Mobiforton
Myospasmal
Tetramdura
Tetrarelax
Musapam
Tethexal
Panos
Rilex
tetrazep von ct
Tetra-saar
MTW-Tetrazepam
Tetrazep AbZ
Tetrazep 1A Pharma
7-chloro-5-(1-cyclohexen-1-yl)-1,3-dihydro-1-methyl-2h-1,4-benzodiazepin-2-one
4621 CB
DTXCID8068549
233-837-7
iqwyaqchyzhjos-uhfffaoysa-n
10379-14-3
Tetrazepam (1mg/ml in Methanol)
DEA No. 2886
7-chloro-5-(cyclohexen-1-yl)-1-methyl-3H-1,4-benzodiazepin-2-one
SCHEMBL157998
CHEMBL2105527
CHEBI:135198
Tetrazepam 0.1 mg/ml in Methanol
Tetrazepam, 1mg/ml in Acetonitrile
CS-6656
DB13324
7-Chloro-5-(1-cyclohexen-1- yl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one
HY-101615
NS00000617
D07277
Q421104
7-Chloro-5-(1-cyclohexen-1-yl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one #
7-chloro-5-(cyclohex-1-en-1-yl)-1-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one