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4-Methylumbelliferone

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Identification
Molecular formula
C11H10O3
CAS number
90-33-5
IUPAC name
7-(dimethylamino)-4-methyl-chromen-2-one
State
State

At room temperature, 4-methylumbelliferone is in a solid state, characterized by its crystalline powder form.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
192.21g/mol
Molar mass
192.2090g/mol
Density
1.3186g/cm3
Appearence

4-Methylumbelliferone appears as a white to off-white crystalline powder. It is notably fluorescent under UV light, emitting a blue fluorescence.

Comment on solubility

Solubility of 7-(dimethylamino)-4-methyl-chromen-2-one

When examining the solubility of 7-(dimethylamino)-4-methyl-chromen-2-one, several factors come into play that can influence its behavior in various solvents. This compound can be characterized as follows:

  • Solvent Polarity: It is generally observed that organic compounds like 7-(dimethylamino)-4-methyl-chromen-2-one tend to be soluble in polar organic solvents such as methanol and ethanol.
  • Water Solubility: Due to its structural components, the compound may have limited solubility in water. The presence of the dimethylamino group can facilitate some degree of hydrogen bonding, but overall aqueous solubility might be low.
  • Solubility in Organic Solvents: It is more likely to exhibit good solubility in nonpolar or slightly polar solvents like chloroform or dichloromethane, making it useful in various organic reactions and extraction processes.

"Like dissolves like" is a useful phrase that highlights the importance of matching the polarity of the solvent with that of the solute. In the case of 7-(dimethylamino)-4-methyl-chromen-2-one, choosing the right solvent will greatly enhance the dissolution process.

In summary, while the solubility profiles of this compound in different solvents can vary significantly, understanding these interactions is crucial for applications in chemical synthesis and analysis. The ability of this compound to dissolve in organic media opens the door to various potential usages in research and industry.

Interesting facts

Interesting Facts about 7-(Dimethylamino)-4-methyl-chromen-2-one

7-(Dimethylamino)-4-methyl-chromen-2-one, often simply referred to as a fluorophore, plays a significant role in the realm of chemical research and applications. This compound belongs to the coumarin family, which is renowned for its diverse array of biological and chemical functions.

Biological Significance

Coumarin derivatives like 7-(dimethylamino)-4-methyl-chromen-2-one are particularly notable for their biological activities:

  • Fluorescence: The compound exhibits strong fluorescent properties, making it valuable in various imaging techniques in biological research.
  • Potential Medicinal Uses: Some studies have suggested potential therapeutic applications, including anti-inflammatory and anti-cancer properties.
  • Photoinactivation: They can be used in photodynamic therapy, targeting cancer cells using light-activated compounds.

Applications in Research

This compound is frequently utilized in several research areas:

  • Biochemistry: Its fluorescent characteristics aid in the visualization of cellular processes.
  • Environmental Chemistry: It can be applied in tracing pollutants and studying environmental degradation.
  • Analytical Chemistry: Used as a dye for various analytical applications.

Synthetic Pathways

The synthesis of 7-(dimethylamino)-4-methyl-chromen-2-one is of great interest in organic chemistry. The process often involves multi-step reactions, highlighting opportunities for chemists to develop new methodologies for generating complex structures.

As researchers continue to unlock the secrets of this compound, it remains a fascinating subject in the intersection of chemistry and biology. Its versatility showcases the endless possibilities in the synthesis and application of organic compounds.

Synonyms
87-01-4
7-(Dimethylamino)-4-methylcoumarin
7-Dimethylamino-4-methylcoumarin
Coumarin 311
2H-1-Benzopyran-2-one, 7-(dimethylamino)-4-methyl-
DAMC
4-Methyl-7-dimethylaminocoumarin
7-(Dimethylamino)-4-methyl-2H-chromen-2-one
7-dimethylamino-4-methylcoumarine
Coumarin, 7-(dimethylamino)-4-methyl-
7-(Dimethylamino)-4-methyl-2-benzopyrone
FBA 52
fluorescent brightener 130
7-(dimethylamino)-4-methylchromen-2-one
4-Methyl-7-(dimethylamino)coumarin
EINECS 201-717-3
NSC 408145
BRN 0169992
TOS1492Q9O
DTXSID6041422
7-(Dimethylamino)-4-methyl-2H-1-benzopyran-2-one
AI3-52502
CALCOFLUOR WHITE LD
NSC-408145
COUMARIN, 7-DIMETHYLAMINO-4-METHYL-
DTXCID4021422
NSC408145
CI FLUORESCENT BRIGHTENER 130
CI 551101
7-N,N-DIMETHYLAMINO-4-METHYLCOUMARIN
7-(Dimethylamino)-4-methylcoumarin (purified by sublimation)
UNII-TOS1492Q9O
MAM-C-7
Coumarin 461
MFCD00006862
7-(dimethylamino)-4-methyl-chromen-2-one
SCHEMBL67970
CHEMBL3186529
TNA35167
Tox21_301534
AKOS015850801
WLN: T66 BOVJ E1 IN1&1
HY-W077359
7-Dimethylamino-4-methyl-chromen-2-one
CAS-87-01-4
NCGC00255493-01
AC-20007
BS-32944
DA-70331
CS-0119819
D3355
D5727
NS00039163
D80429
7-(Dimethylamino)-4-methyl-2H-chromen-2-one #
Q27290094