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Notch signaling inhibitor

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Identification
Molecular formula
C23H32N4O4S2
CAS number
144796-12-5
IUPAC name
7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
State
State

At room temperature, the compound is typically in a solid state. Its crystalline form is stable under ambient conditions, making it a suitable candidate for laboratory handling and further chemical analysis.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
523.50
Boiling point (Kelvin)
796.65
General information
Molecular weight
488.66g/mol
Molar mass
487.6680g/mol
Density
1.3100g/cm3
Appearence

The compound exhibits a crystalline solid appearance. The color typically ranges from off-white to light tan, indicating the presence of sulfur moieties within the structure. It is usually opaque and uniform in texture.

Comment on solubility

Solubility of 7-Ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

The solubility of a compound can provide valuable insights into its chemical behavior and potential applications. For the compound 7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone (C23H32N4O4S2), we can consider several factors that influence solubility:

  • Polar vs. Nonpolar Properties: The presence of both thiol (S) and nitrogen (N) functional groups can contribute to polar characteristics, which may enhance solubility in polar solvents.
  • Complex Structure: The bicyclic structure may introduce steric hindrance, potentially impacting its ability to dissolve in various solvents.
  • Temperature Effects: Solubility often increases with higher temperatures, and it would be beneficial to investigate its solubility across a range of temperatures.
  • Common Solvents: It is likely more soluble in solvents like methanol or ethanol compared to nonpolar solvents like hexane.

Determining the exact solubility would require experimental measurement, but considering the factors above can aid in predicting its behavior in different environments. As a general rule, understanding solubility is crucial in fields such as pharmacology, environmental science, and material science, where solubility can dictate the effectiveness or stability of compounds.

Interesting facts

Exploring 7-Ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

This intriguing compound, known as 7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone, showcases a fascinating interplay of structure and functionality that makes it a subject of interest in the field of organic and medicinal chemistry.

Key Characteristics

  • Structural Complexity: The compound features a unique bicyclic system, integrated with multiple functional groups including oxo, thioether, and tetrazole moieties that contribute to its chemical versatility.
  • Potential Applications: Due to its complex structure, it may exhibit interesting biological activities, making it a potential candidate for drug development and therapeutic applications.
  • Synthetic Routes: The synthesis of such complex organic molecules can provide insights into novel synthetic methodologies and can challenge chemists to innovate new reactions.
  • Intermolecular Interactions: The diverse functional groups within the molecule may participate in various intermolecular interactions, influencing its reactivity and properties.

"The beauty of chemistry lies in its complexity and the endless possibility of creating new compounds that may hold the keys to advancements in medicine and technology."

Research Directions

  • Investigating the reaction mechanisms that underpin the synthesis of this compound can lead to greater understanding in the field of synthetic organic chemistry.
  • Exploring the compound's potential pharmacological properties may reveal its efficacy against various biological targets.
  • Studying the physical properties of the compound in various environments may unveil unique characteristics that could be harnessed in materials science.

The exploration of 7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone offers a promising glimpse into the world of complex organic molecules, where each carbon and nitrogen atom can tell a story about potential new discoveries.

Synonyms
128517-07-7
7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
Romidepsin (FK228; Depsipeptide)
FK 228;FR 901228;NSC 630176
Neuro_000275
CHEMBL2130995
HMS3656D16
AKOS032960428
DA-33627
NCI60_009796
7-ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl] Cyclic (35)-Disulfide