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7-Fluoroheptan-1-ol

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Identification
Molecular formula
C7H15FO
CAS number
408-27-5
IUPAC name
7-fluoroheptan-1-ol
State
State

At room temperature, 7-Fluoroheptan-1-ol is in a liquid state.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
199.00
Boiling point (Kelvin)
472.15
General information
Molecular weight
134.19g/mol
Molar mass
134.1870g/mol
Density
0.9673g/cm3
Appearence

7-Fluoroheptan-1-ol is a colorless liquid with a mild alcohol-like odor. It is typically clear in appearance and can become slightly viscous.

Comment on solubility

Solubility of 7-Fluoroheptan-1-ol

7-Fluoroheptan-1-ol, a compound featuring a fluorine atom attached to a heptane chain, exhibits intriguing solubility characteristics. This compound is an alcohol, and its solubility is influenced by the balance between its hydrophilic (water-attracting) and hydrophobic (water-repelling) properties.


Solubility Characteristics:

  • Polar Nature: The hydroxyl group (-OH) in 7-fluoroheptan-1-ol is polar, which enhances its solubility in polar solvents like water.
  • Alkyl Chain Length: With a heptane chain, the compound's larger hydrophobic alkyl portion may reduce solubility compared to shorter-chain alcohols.
  • Effect of Fluorine: The electronegative fluorine can alter the compound’s overall interactions, potentially increasing solubility in certain organic solvents.

In summary, 7-fluoroheptan-1-ol is likely to be:

  1. Soluble in polar solvents such as water due to its alcohol functional group.
  2. Partially soluble in non-polar solvents, influenced by the hydrophobic heptane part of the molecule.

Thus, while it has a degree of water solubility, its overall behavior in various solvents can be fascinatingly unique, highlighting the delicate interplay of hydrophilicity and hydrophobicity that governs solubility.

Interesting facts

Interesting Facts About 7-Fluoroheptan-1-ol

7-Fluoroheptan-1-ol is a fascinating compound that merges the characteristics of alcohols with the unique properties imparted by the presence of fluorine. Here are some intriguing aspects of this compound:

  • Fluorination Effect: The introduction of a fluorine atom can significantly influence the chemical behavior of organic compounds. Fluorine is electronegative, which can enhance lipophilicity and alter the solubility, making this compound of interest in medicinal chemistry.

  • Synthetic Versatility: 7-Fluoroheptan-1-ol is often used as an intermediate in organic synthesis. The presence of the alcohol functional group allows for further chemical transformations, including esterification and etherification.

  • Biological Relevance: Compounds like 7-fluoroheptan-1-ol have potential applications in pharmaceuticals, particularly in the design of new drugs that may target specific receptors or enzymes in the body.

  • Research Applications: This compound serves as a valuable probe in studying the interactions of fluorinated compounds with biological systems, enhancing our understanding of how fluorine-modified molecules behave in various environments.

  • Chirality Exploration: Depending on the synthesis route, 7-fluoroheptan-1-ol can exhibit differences in optical activity, making it an intriguing subject for studies on chirality and stereochemistry.

In conclusion, 7-fluoroheptan-1-ol is not just a simple alcohol but a compound rich in potential that invites further exploration in both laboratory settings and industrial applications. Its unique structural characteristics pave the way for exciting discoveries in the realm of chemistry.

Synonyms
7-fluoroheptan-1-ol
408-16-2
7-fluoro-1-heptanol
HEPTANOL, 7-FLUORO-
7-fluoro-heptan-1-ol
7-Fluoroheptanol
omega-Fluoroheptanol
BRN 1697749
4-01-00-01736 (Beilstein Handbook Reference)
SCHEMBL1627447
DTXSID80193787