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Resazurin

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Identification
Molecular formula
C12H6NNaO4
CAS number
62758-13-8
IUPAC name
7-hydroxy-10-oxido-phenoxazin-10-ium-3-one
State
State

At room temperature, resazurin is in a solid state.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
229.20g/mol
Molar mass
229.1990g/mol
Density
1.4205g/cm3
Appearence

Resazurin is an orange to pinkish crystalline powder. It has a vibrant appearance and is often used in solution, where it imparts a blue color due to its oxidized form.

Comment on solubility

Solubility of 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one

The solubility of 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one is a fascinating topic due to its diverse range of applications in the field of chemistry and biochemistry.

This compound displays a moderate level of solubility in various solvents. Key points regarding its solubility include:

  • Polar Solvents: It tends to dissolve well in polar solvents such as water and methanol due to the presence of hydroxyl groups which can form hydrogen bonds.
  • Non-Polar Solvents: In non-polar solvents, the solubility of this compound is considerably lower, making it less favorable for use in non-polar environments.
  • Temperature Dependence: The solubility is also influenced by temperature; higher temperatures generally increase solubility.

Moreover, it is important to consider various factors that can affect solubility:

  1. pH Levels: The solubility can vary with changes in pH, which can influence ionization states.
  2. Concentration of Solute: The degree of saturation is crucial; oversaturation can lead to precipitation.

As highlighted, "understanding the solubility of compounds like 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one is essential for their effective application in laboratory and industrial processes." This compound's unique properties make it valuable, particularly in biochemical assays or dye applications where solubility plays a critical role.

Interesting facts

Interesting Facts about 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one

7-hydroxy-10-oxido-phenoxazin-10-ium-3-one, often referred to simply as a phenoxazine derivative, is a remarkable compound that belongs to a class of dyes and has garnered significant attention in various fields of research, especially in the realm of biochemistry and medicinal chemistry. Here are some fascinating facts about this compound:

  • Biological Activities: Phenoxazines have been shown to exhibit a range of biological activities, including antibacterial, antifungal, and antiviral properties. This makes compounds like 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one valuable for potential therapeutic applications.
  • Role as a Fluorescent Probe: This compound's structural characteristics enable it to act as a fluorescent probe, which is instrumental in cellular imaging studies. Researchers can track cellular processes with enhanced precision due to its fluorescent properties.
  • Colorimetric Applications: The intense color produced by phenoxazines allows them to be used in colorimetric assays. This feature is exploited in various analytical chemistry techniques for the detection of specific analytes.
  • Historical Significance: Compounds in this class have a rich history, dating back to their use in the development of dyes. Their vibrant colors made them a popular choice in the textile industry before their medicinal properties were explored.
  • Innovative Research: Ongoing studies are investigating the use of phenoxazines in targeted drug delivery systems and cancer therapeutics. The ability of these compounds to be modified for improved effectiveness and reduced toxicity is a promising avenue for future research.

In summary, 7-hydroxy-10-oxido-phenoxazin-10-ium-3-one exemplifies the intersection of chemistry and biology, serving as both a functional material in laboratory applications and a compound of interest in medicinal research. The versatility of this compound is a key reason why scientists continue to explore its potential across various domains.

Synonyms
RESAZURIN
550-82-3
Diazoresorcinol
Azoresorcin
Resazoin
Resazurine
Alamar blue
7-Hydroxy-3H-phenoxazin-3-one 10-oxide
EINECS 208-987-1
NSC 10438
UNII-1FN9YD6968
BRN 0221382
RHODALUX
153796-08-8
1FN9YD6968
RESAZURIN [MI]
7-Hydroxy-3H-fenoxazin-3-on-10-oxid [Czech]
NSC-10438
NSC-56323
7-Hydroxy-3H-fenoxazin-3-on-10-oxid
DTXSID4060280
4-27-00-03594 (Beilstein Handbook Reference)
7-hydroxy-10-oxido-phenoxazin-10-ium-3-one
7-HYDROXY-3H-PHENOXAZINE-3-ONE 10-OXIDE
reazurin
reazurine
7Hydroxy3Hfenoxazin3on10oxid
DTXCID3041823
7Hydroxy3Hphenoxazin3one 10oxide
3HPhenoxazin3one, 7hydroxy, 10oxide
7-hydroxy-10-oxidophenoxazin-10-ium-3-one
7-Hydroxy-3-oxo-3H-phenoxazine 10-oxide
CHEBI:8806
3H-Phenoxazin-3-one, 10-oxide
WLN: T C666 BN FV IOJ BO LQ
3H-Phenoxazin-3-one,7-hydroxy-, 10-oxide
3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide
MFCD00066739
MolMap_000044
SCHEMBL6338
SCHEMBL1502340
CHEMBL1616414
PLXBWHJQWKZRKG-UHFFFAOYSA-N
GLXC-04913
NSC10438
NSC56323
7-Hydroxy-3-oxo-3H-phenoxazine10-oxide
BS-28553
DA-49598
NCI60_000106
HY-118540
CS-0066314
NS00021208
D84267
7-hydroxy-3-oxo-3H-phenoxazin-10-ium-10-olate
Q409628