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Arecoline hydrochloride

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Identification
Molecular formula
C8H13NO2Cl
CAS number
300-08-3
IUPAC name
[7-(hydroxymethyl)-1,2,3,4,5,8-hexahydropyrrolizin-4-ium-1-yl] 2-methylbut-2-enoate;chloride
State
State
In its common state as a hydrochloride salt, arecoline hydrochloride is typically seen as a solid at room temperature, often in crystalline powder or granular form.
Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
286.80
Boiling point (Kelvin)
560.00
General information
Molecular weight
203.69g/mol
Molar mass
203.6890g/mol
Density
1.0610g/cm3
Appearence

Arecoline hydrochloride appears as a white to pale yellow crystalline powder, sometimes observed in a more granular form depending on the specific manufacturing and processing.

Comment on solubility

Solubility Overview

The compound [7-(hydroxymethyl)-1,2,3,4,5,8-hexahydropyrrolizin-4-ium-1-yl] 2-methylbut-2-enoate; chloride is an intriguing substance when it comes to its solubility characteristics. Understanding its solubility is crucial for applications ranging from pharmaceuticals to industrial processes.

Factors Influencing Solubility

Several factors contribute to the overall solubility of this compound:

  • Polarity: The presence of the hydroxymethyl group implies that it can engage in hydrogen bonding, which may enhance its solubility in polar solvents.
  • Ionic Nature: Being a chloride, the ionic interactions can significantly affect solubility in water and other polar solvents.
  • Temperature: Like many compounds, solubility can be temperature-dependent; thus, higher temperatures might increase solubility.

Solvent Compatibility

This compound is likely to be more soluble in:

  • Water: Due to the polar functional groups present.
  • Alcohols: Such as ethanol or isopropanol owing to similar polar characteristics.

Conclusion

In summary, the solubility of [7-(hydroxymethyl)-1,2,3,4,5,8-hexahydropyrrolizin-4-ium-1-yl] 2-methylbut-2-enoate; chloride is influenced by its molecular structure and the interactions of its functional groups. It is essential to consider the solvent system and environmental conditions when assessing its solubility.

Interesting facts

Interesting Facts about 7-(hydroxymethyl)-1,2,3,4,5,8-hexahydropyrrolizin-4-ium-1-yl 2-methylbut-2-enoate; chloride

This intriguing compound, with its multifaceted structure, has garnered attention in various fields of research, particularly in organic chemistry and pharmacology. Here are some notable points:

  • Structural Complexity: The compound features a hexahydropyrrolizin moiety, which is quite significant in the study of nitrogen-containing heterocycles. This structural complexity often imparts unique chemical properties that can be exploited in synthetic challenges.
  • Functional Groups: With the presence of both hydroxymethyl and ester functionality, this compound presents diverse reactivity paths, enabling its application in synthesis and as an intermediate.
  • Biological Relevance: Research indicates that derivatives of pyrrolizidine compounds can exhibit varied biological activities, including potential medicinal applications. The cationic nature due to the quaternized nitrogen can enhance interactions with biological membranes, marking its relevance in drug design.
  • Versatile Applications: This compound may find applications in:
    • As a precursor in the synthesis of complex molecules.
    • In the study of ion exchange processes due to its chloride component.
    • In agricultural chemistry for developing formulations that could influence herbicidal or pesticide properties.
  • Unique Properties: Its ionic nature may contribute to interesting solvation properties, enhancing its role in various chemical environments when mixed with solvents.

In summary, the nuanced characteristics of 7-(hydroxymethyl)-1,2,3,4,5,8-hexahydropyrrolizin-4-ium-1-yl 2-methylbut-2-enoate; chloride not only enrich our understanding of organic compounds but also pave the way for future research and application possibilities in various scientific domains. As noted in a recent study, "the blend of structural diversity and reactivity potential makes such compounds invaluable in advancing both theoretical and practical chemistry."