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notropis

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Identification
Molecular formula
C13H19NO3
CAS number
22144-77-0
IUPAC name
[7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-yl] 2-methylbut-2-enoate
State
State

At room temperature, notropis is typically in a solid state, specifically appearing as a crystalline solid.

Melting point (Celsius)
118.50
Melting point (Kelvin)
391.65
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
221.30g/mol
Molar mass
221.2990g/mol
Density
1.1570g/cm3
Appearence

The compound appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of [7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-yl] 2-methylbut-2-enoate

The solubility of the compound [7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-yl] 2-methylbut-2-enoate can be intricately influenced by several factors:

  • Polarity: The hydroxymethyl group introduces some polarity, which may enhance solubility in polar solvents such as water.
  • Hydrophobic Character: Given the presence of the hydrocarbon moiety originating from 2-methylbut-2-enoate, the compound may have hydrophobic characteristics that could limit its solubility in highly polar solvents.
  • Temperature: As with many organic compounds, an increase in temperature may improve solubility due to increased molecular motion and reduced intermolecular forces.
  • pH Levels: The local pH can also play a vital role, particularly if the compound can ionize or interact differently under varying acidity or basicity.

Overall, while it is challenging to pinpoint a precise solubility without empirical data, one could conjecture that this compound may exhibit moderate solubility in a variety of solvents due to its unique structure. As stated, "A solute must dissolve to play a role!" thus underlying the importance of solubility in applications ranging from pharmacology to chemical synthesis.

Interesting facts

Interesting Facts about [7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-yl] 2-methylbut-2-enoate

This fascinating compound, more commonly known in the realm of medicinal chemistry, showcases a unique structure that combines a pyrrolidine base with a methylbutenoate moiety. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound features a tetrahydro-pyrrolizin framework, which significantly contributes to its pharmacological properties. The presence of hydroxymethyl groups plays a critical role in modulating its biological activity.
  • Potential Biological Applications: Research indicates potential therapeutic effects of this class of compounds in various fields, including neuropharmacology and medicinal chemistry. The intricate structure offers points of attachment for further modifications that could enhance efficacy.
  • Chemical Versatility: The double bond in the 2-methylbutenoate part of the molecule presents opportunities for various chemical reactions, enabling the development of derivatives that may exhibit enhanced bioactivity or different properties.
  • Consideration in Design: In drug design, it's crucial to understand how subtle structural changes can impact a compound's interaction with biological targets. The hydroxymethyl group, for instance, can influence hydrogen bonding and solubility characteristics.
  • Inspiring Synthetic Approaches: Chemists often seek innovative synthetic methodologies to produce such specialized compounds, utilizing techniques such as asymmetric synthesis and advanced coupling reactions to ensure purity and yield.

As emphasized by chemists in the field, “Understanding the intricate relationship between molecular structure and biological activity is key to advancing pharmaceutical development.” This compound exemplifies the importance of such studies and remains a point of interest in ongoing research.

Synonyms
7-Angeloylretronecine
GAA02982