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Isopropoxyphenylchromone

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Identification
Molecular formula
C18H16O3
CAS number
23552-68-3
IUPAC name
7-isopropoxy-2-phenyl-chromen-4-one
State
State

At room temperature, Isopropoxyphenylchromone is in a solid state. It is usually found in a crystalline form, typical of many chromone derivatives.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.20
Boiling point (Celsius)
479.50
Boiling point (Kelvin)
752.70
General information
Molecular weight
278.32g/mol
Molar mass
278.3180g/mol
Density
1.1897g/cm3
Appearence

Isopropoxyphenylchromone typically appears as a pale yellow crystalline solid. Its appealing hue is due to the chromone structure, which often confers subtle coloration to compounds of this class.

Comment on solubility

Solubility of 7-isopropoxy-2-phenyl-chromen-4-one

7-isopropoxy-2-phenyl-chromen-4-one, with the chemical formula C18H16O3, exhibits noteworthy solubility characteristics that can be summarized as follows:

  • Solvent Dependence: The solubility of this compound is significantly influenced by the choice of solvent. It tends to be soluble in organic solvents such as ethanol, methanol, and ethyl acetate.
  • Polar vs. Non-polar: Due to the presence of the isopropoxy group, there is an emphasis on its solubility in non-polar to moderately polar solvents, while it generally shows low solubility in water.
  • Poor Aqueous Solubility: The hydrophobic regions of the molecule limit its ability to dissolve in aqueous solutions. This is a common characteristic of many chromen-4-one derivatives.

As indicated by these factors, the solubility behavior of 7-isopropoxy-2-phenyl-chromen-4-one can be described as relatively complex, depending on various environmental conditions. The importance of solvent polarity and molecular structure in determining solubility cannot be overstated. Understanding these properties is crucial for practical applications in fields such as pharmaceuticals and organic chemistry.

Interesting facts

Interesting Facts about 7-Isopropoxy-2-phenyl-chromen-4-one

7-Isopropoxy-2-phenyl-chromen-4-one is a fascinating compound that belongs to the flavonoid family, known for their wide range of biological activities. Here are some intriguing details about this compound:

  • Flavonoid Derivative: This compound is a derivative of flavones, characterized by its chromone structure, which is a benzopyranone. Flavonoids themselves are well-known for their antioxidant properties, contributing significantly to human health.
  • Biological Activities: Research has indicated that compounds similar to 7-isopropoxy-2-phenyl-chromen-4-one exhibit various biological activities, including:
    • Antioxidant effects
    • Anti-inflammatory properties
    • Potential anticancer effects
  • Medicinal Properties: Structurally, 7-isopropoxy-2-phenyl-chromen-4-one may interact with enzyme systems, providing a basis for drug development in treating diseases associated with oxidative stress and inflammation.
  • In Nature: Many flavonoids are found in plants, contributing to their color and attracting pollinators. They also play a role in protecting plants from UV radiation and pathogens.
  • Synthetic Pathways: The synthesis of flavonoids like this compound can involve various methods, including cyclization reactions, which are of great interest in organic chemistry and pharmacology.

Overall, 7-isopropoxy-2-phenyl-chromen-4-one exemplifies the intricate connection between chemical structure and biological function, making it a compelling topic for study in both academic and pharmaceutical research settings.

Synonyms
2-phenyl-7-(propan-2-yloxy)-4h-chromen-4-one
2-phenyl-7-propan-2-yloxychromen-4-one
ipraflavone
Spectrum_000012
Spectrum3_001726
Spectrum4_000129
Spectrum5_000896
BSPBio_003372
KBioGR_000518
KBioSS_000352
DivK1c_000133
SPECTRUM1400010
CHEMBL1372514
HMS500G15
KBio1_000133
KBio2_000352
KBio2_002920
KBio2_005488
KBio3_002592
NINDS_000133
YVLFFUSZFGCFFW-UHFFFAOYSA-N
Pharmakon1600-01400010
Tox21 111532
NSC755888
CCG-213750
IDI1_000133
NCGC00095872-02
NCGC00178109-01
SBI-0051267.P002
7-(1-Methylethoxy)-2-phenyl-4H-chromen-4-one
AB00051903_02
SR-01000872735
SR-01000872735-1
BRD-K36646537-001-01-3
BRD-K36646537-001-02-1