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Harmaline hydrochloride

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Identification
Molecular formula
C14H15ClN2O
CAS number
6027-58-5
IUPAC name
7-methoxy-1-methyl-2H-pyrido[3,4-b]indole;hydrochloride
State
State

At room temperature, harmaline hydrochloride exists as a solid.

Melting point (Celsius)
275.00
Melting point (Kelvin)
548.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
266.73g/mol
Molar mass
266.7330g/mol
Density
1.2000g/cm3
Appearence

Harmaline hydrochloride typically appears as a crystalline powder that is white to off-white in color. It is often used in chemistry and pharmacology settings and demonstrates good solubility in water.

Comment on solubility

Solubility of 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole;hydrochloride

The solubility of 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole;hydrochloride in various solvents can provide critical insights into its potential applications and efficacy. Typically, the solubility of hydrochloride salts is influenced by several factors:

  • Polarity of the Solvent: This compound is expected to be more soluble in polar solvents such as water compared to non-polar solvents.
  • pH: The ionization state can be altered by pH changes, which might improve the solubility of the hydrochloride form.
  • Temperature: Higher temperatures often enhance solubility, which can be an important consideration in experimental settings.

According to general solubility principles:

  1. Like dissolves like: Compounds with similar polarities tend to be more soluble in each other.
  2. Hydrochloride salts: Generally exhibit better water solubility due to their ionized nature.
  3. Solvate formation: The presence of hydrogen bonding can further enhance the solubility in certain solvents.

In conclusion, while specific solubility data for 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole;hydrochloride may vary, it is anticipated to be soluble in aqueous solutions, making it versatile for various pharmaceutical formulations. Additional experiments and assessments may provide a clearer picture of its solubility profile under various conditions.

Interesting facts

Interesting Facts about 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole Hydrochloride

7-methoxy-1-methyl-2H-pyrido[3,4-b]indole hydrochloride is a fascinating compound that has garnered attention for its unique structure and potential applications. Here are some interesting aspects of this compound:

  • Complex Structure: This compound features a distinctive fused ring system, consisting of both pyridine and indole moieties. Such a structure is indicative of a rich chemical landscape that can lead to various biological activities.
  • Potential Biological Activity: Research has suggested that compounds with indole and pyridine structures often exhibit interesting pharmacological properties. This has drawn interest in medicinal chemistry for the development of new therapeutic agents.
  • Research Studies: Scientists are actively exploring the implications of this compound in neuropharmacology. Initial studies may hint at effects on neural pathways, which can be crucial for understanding mood disorders or cognitive function.
  • Synthetic Pathways: The synthesis of 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole is of particular interest in organic chemistry for its ability to showcase various methodologies and techniques employed in the construction of complex organic molecules.
  • Mechanistic Insights: The unique functionality of the methoxy group at position 7 may play a significant role in influencing the compound’s reactivity and interaction with biological targets, making it an attractive subject for mechanistic studies.

In summary, 7-methoxy-1-methyl-2H-pyrido[3,4-b]indole hydrochloride stands as an exciting example of the intersection between structural chemistry and biological applications. Its complex molecular architecture not only piques the interest of chemists but also reflects pathways towards potential therapeutic exploration.