Skip to main content

Harmaline

ADVERTISEMENT
Identification
Molecular formula
C13H14N2O
CAS number
442-51-3
IUPAC name
7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole
State
State

At room temperature, Harmaline is in a solid state, typically appearing as a crystalline material.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.00
Boiling point (Celsius)
331.00
Boiling point (Kelvin)
604.00
General information
Molecular weight
214.27g/mol
Molar mass
214.2600g/mol
Density
1.3000g/cm3
Appearence

Harmaline is typically seen as a white to yellow crystalline solid. It may appear as a fine powder or shiny crystalline flakes and is often used for its psychoactive properties.

Comment on solubility

Solubility Characteristics of 7-Methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole

The solubility of 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole (C13H14N2O) can be influenced by several factors:

  • Polarity: The presence of an –OCH3 (methoxy) group enhances the compound's polarity, potentially increasing its solubility in polar solvents.
  • Solvent Type: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), compared to water.
  • Temperature: Increased temperature often leads to enhanced solubility for many organic compounds, making higher temperatures beneficial when dissolving this pyridoindole derivative.
  • Concentration: The phenomenon of solubility can also be concentration-dependent, where higher concentrations might lead to precipitation in solubility-limited solutions.

Overall, the solubility of 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole emphasizes the intricate balance of chemical properties that dictate solubility in various environments. Understanding these interactions is essential for both application and research purposes.

Interesting facts

Interesting Facts about 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole

7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole, a compound with a unique structure, is gaining attention in the realm of medicinal chemistry due to its potential biological activities. Here are some fascinating aspects to consider:

  • Structural Significance: This compound features a pyridoindole framework, which combines two aromatic systems—pyridine and indole. This structural configuration may be responsible for its intriguing biological properties.
  • Potential Pharmacological Properties: Compounds related to the indole family have been noted for various pharmacological effects, including anti-inflammatory and neuroprotective activities. Research into this specific compound may uncover valuable therapeutic applications.
  • Natural Product Inspiration: The indole structure is commonly found in many natural products, including essential amino acids and a variety of alkaloids. This compound's design may be influenced by naturally occurring compounds, giving it a potential pioneering role in drug design.
  • Research Studies: Initial studies suggest that derivatives of the pyridoindole structure can interact with specific receptors in the brain, which could make them candidates for treating neurological disorders.
  • Future Directions: As with many compounds in drug discovery, understanding the molecular interactions of 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole could pave the way for novel therapeutic developments. Continuous research is warranted to explore its properties and effects.

Given its innovative structure and potential as a bioactive agent, 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole exemplifies the synthesis of chemistry and pharmacology. As scientists continue to explore its capabilities, we may well uncover its role in advancing health and medicine.

Synonyms
harmaline
304-21-2
Dihydroharmine
Harmidine
Armalin
3,4-Dihydroharmine
Harmalol methyl ether
O-Methylharmalol
Harmine, dihydro-
3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole
harmalin
NSC 407285
1-Methyl-7-methoxy-3,4-dihydro-beta-carboline
Dihydro-Harmine
UNII-CN58I4TOET
3H-Pyrido(3,4-b)indole, 4,9-dihydro-7-methoxy-1-methyl-
CN58I4TOET
7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline
EINECS 206-152-6
4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido(3,4-b)indole
BRN 0207310
3, 4-Dihydroharmine
CHEBI:28172
HSDB 7645
3,4-Dihydro-7-methoxy-1-methyl-9-pyrid(3,4-b)indole
3,4-Dihydro-7-methoxy-1-methyl-9-pyrido(3,4-b)indole
4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
HARMALINE [MI]
HARMALINE [HSDB]
MFCD00004955
HARMALINE [MART.]
NSC-407285
MLS000028746
CHEMBL340807
DTXSID8041038
7-methoxy-1-methyl-4,9-dihydro-3H-b-carboline
1-Methyl-7-methoxy-3,4-dihydro-.beta.-carboline
TNP00101
SMR000058221
3,4-Dihydro-7-methoxy-1-methyl-b-carboline
HARMALINE (MART.)
3,4-Dihydro-7-methoxy-1-methyl-9-pyrid[3,4-b]indole
3,4-Dihydro-7-methoxy-1-methyl-9H-pyrid[3,4-b]indole
7-METHOXY-1-METHYL-4,9-DIHYDRO-3H-PYRIDO(3,4-B)INDOLE
3,4-Dihydroharmin
SR-01000721899
3,4-Dihydro-7-methoxy-1-methyl-9H-pyrid(3,4-b)indole
3,4-b]indole
Spectrum_000301
Opera_ID_665
Prestwick0_000610
Prestwick1_000610
Prestwick2_000610
Prestwick3_000610
Spectrum2_000411
Spectrum3_000720
Spectrum4_000824
Spectrum5_001452
7-methoxy-1-methyl-3,4-dihydrobeta-carboline
1-Methyl-7-methoxy-3,4-dihydro- beta-carboline
Oprea1_112644
BSPBio_000520
BSPBio_002539
KBioGR_001367
KBioSS_000781
MLS001148231
BIDD:ER0444
DivK1c_000950
SCHEMBL199260
SPECTRUM1500864
SPBio_000362
SPBio_002739
BPBio1_000572
MEGxp0_001874
SCHEMBL3862598
DTXCID6021038
ACon1_000019
CHEBI:95328
GTPL13140
HMS502P12
KBio1_000950
KBio2_000781
KBio2_003349
KBio2_005917
KBio3_001759
NINDS_000950
HMS1921K22
HMS2233L23
HMS3371G17
HMS3885P22
BDBM50029799
CCG-38677
NSC407285
NSC789037
s4776
STL570451
AKOS015904564
AKOS026750619
DB13875
FH52430
KS-5325
NSC-789037
SDCCGMLS-0066716.P001
IDI1_000950
NCGC00017221-01
NCGC00017221-02
NCGC00017221-03
NCGC00017221-04
NCGC00017221-05
NCGC00017221-06
NCGC00017221-07
NCGC00017221-10
NCGC00094867-01
NCGC00094867-02
NCGC00094867-03
NCGC00094867-04
NCGC00094867-05
NCGC00094867-06
AC-34436
LS-14204
PD056221
WLN: T B656 DM HM CHJ F1 KO1
DB-047778
HY-107828
CS-0030704
H1237
NS00017928
3,4-Dihydro-7-methoxy-1-methyl-beta-carboline
C06536
1-Methyl-7-methoxy-3, 4-dihydro-beta-carboline
1-Methyl-7-methoxy-3,4-dihydro-beta -carboline
1-Methyl-7-methoxy-3, 4-dihydro-beta -carboline
3H-Pyrido[3, 4,9-dihydro-7-methoxy-1-methyl-
7-Methoxy-1-methyl-4,9-dihydro-3H-?-carboline
7-Methoxy-1-methyl-4,9-dihydro-3H-I2-carboline
Q135270
7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline
7-methoxy-1-methyl-3,4-dihydro-2h-beta-carboline
A1-00783
SR-01000721899-4
SR-01000721899-5
7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline #
BRD-K91317041-001-03-8
BRD-K91317041-310-03-3
3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
1-Methyl-7-methoxy-3,4-dihydro-b-carboline;3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
206-152-6