Harmaline hydrochloride | Solubility of Things

Identification

Molecular formula

C₁₃H₁₅N₂OCl

CAS number

6027-95-4

IUPAC name

7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium;chloride

State

Harmaline hydrochloride is in a solid crystalline state at room temperature. It is generally stable under ambient conditions but should be stored in airtight containers to prevent moisture absorption.

Melting point (Celsius)

269.00

Melting point (Kelvin)

542.00

Boiling point (Celsius)

280.00

Boiling point (Kelvin)

553.00

General information

Molecular weight

278.77g/mol

Molar mass

278.7680g/mol

Density

1.3000g/cm³

Appearence

Harmaline hydrochloride typically appears as an off-white to light yellow crystalline powder. It is a water-soluble salt form derived from harmaline and shows mild fluorescence under ultraviolet light.

Comment on solubility

Solubility of 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium chloride

The solubility of 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium chloride can be influenced by various factors, and understanding these can be quite fascinating. Here are some key points:

Polar nature: The presence of the chloride ion suggests a degree of ionic character, which typically enhances solubility in polar solvents like water.
Solvent dependence: Compounds like this often show differing solubility profiles in various solvents:

Highly soluble in polar solvents (e.g., water, ethanol)
Moderate to low solubility in non-polar solvents (e.g., hexane, toluene)

Structural influence: The methoxy and pyrido-indole moieties can influence solubility by impacting steric and electronic factors.
Temperature effects: As with many chemical compounds, solubility can increase with temperature, making it important to consider operational conditions.

In conclusion, while 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium chloride exhibits good solubility in specific polar solvents, the overall behavior depends on its environment and conditions. Always consider the nature of the solvent and the temperature when assessing solubility properties.

Interesting facts

Interesting Facts about 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium;chloride

The compound 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium;chloride belongs to a fascinating class of chemicals known as pyridinium salts. These compounds often exhibit unique properties and play various roles in biological systems, making them of significant interest in both organic chemistry and pharmacology.

Key Features of the Compound

Biological Relevance: Many pyridinium salts, including this compound, have been studied for their potential biological activities, particularly in relation to neurochemistry and their effects on neurotransmitter systems.
Potential Therapeutic Uses: Certain derivatives of pyridinium compounds show promise in treating neurodegenerative diseases due to their interaction with neural pathways.
Synthesis Pathways: The synthesis of compounds structurally similar to 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium;chloride often involves complex organic reactions, providing challenges and opportunities for chemists to explore new synthetic methodologies.
Jungian Influence: The indole moiety present in the structure has been a subject of interest in literature and psychology, particularly within the context of Carl Jung's theories of archetypes and the collective unconscious.

One interesting aspect of this compound is its structural complexity. The pyrido[3,4-b]indole framework presents a blend of aromatic and heteroaromatic characteristics, which can lead to diverse electronic properties. As a chemist, understanding how these structural elements influence both chemical reactivity and biological interactions can be incredibly rewarding.

In conclusion, 7-methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-ium;chloride is not just a chemical entity; it is a gateway into a realm of biological research and organic synthesis that continues to expand our understanding of chemistry's interplay with life itself.

Synonyms

6028-02-0