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Piperonal

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Identification
Molecular formula
C8H6O3
CAS number
120-57-0
IUPAC name
7-methoxy-1,3-benzodioxole-5-carbaldehyde
State
State

Solid at room temperature.

Melting point (Celsius)
37.00
Melting point (Kelvin)
310.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
150.15g/mol
Molar mass
150.1480g/mol
Density
1.2093g/cm3
Appearence

Piperonal is a white solid that forms needle-like crystals. It has a vanilla-like aroma.

Comment on solubility

Solubility of 7-methoxy-1,3-benzodioxole-5-carbaldehyde

7-methoxy-1,3-benzodioxole-5-carbaldehyde exhibits interesting solubility characteristics, primarily influenced by its molecular structure. Understanding its solubility helps in various applications, including synthesis and formulation. Here are some key points:

  • Polar Nature: The presence of a carbonyl group and ether functionality contributes to moderate polarity, allowing it to dissolve well in polar solvents.
  • Solvent Compatibility: Typically, 7-methoxy-1,3-benzodioxole-5-carbaldehyde is soluble in dimethyl sulfoxide (DMSO), ethanol, and methanol, making these solvents suitable for laboratory use.
  • Limited Solubility in Water: Due to its relatively large structure and hydrophobic aromatic segments, its solubility in water is quite limited.
  • Temperature Dependency: Like many organic compounds, solubility may increase with rising temperatures, aiding in dissolution.

In conclusion, while 7-methoxy-1,3-benzodioxole-5-carbaldehyde is soluble in various organic solvents, it displays a limited affinity for water due to its structural characteristics. This solubility profile is essential for its applications in chemical synthesis and research.

Interesting facts

Interesting Facts About 7-Methoxy-1,3-benzodioxole-5-carbaldehyde

7-Methoxy-1,3-benzodioxole-5-carbaldehyde is a fascinating organic compound that belongs to the family of benzodioxoles, which are well-known for their diverse applications in medicinal chemistry and organic synthesis. Here are some intriguing aspects of this compound:

  • Natural Occurrence: Compounds similar to 7-methoxy-1,3-benzodioxole-5-carbaldehyde are often found in nature, particularly within various plant species. This compound can be associated with the rich chemistry of natural products.
  • Biological Activity: This compound is of interest due to its potential biological activities. Many derivatives of benzodioxole compounds exhibit various activities, including anti-inflammatory and antioxidant effects, making them valuable in pharmacological research.
  • Reactiveness: The aldehyde functional group present in this compound is highly reactive, making 7-methoxy-1,3-benzodioxole-5-carbaldehyde an important intermediate in organic synthesis. It can be utilized to create a variety of other chemical entities through condensation reactions.
  • Research Applications: Scientists are increasingly exploring the applications of benzodioxoles in designing new pharmaceuticals. This means that compounds like 7-methoxy-1,3-benzodioxole-5-carbaldehyde are under continuous investigation for their possible therapeutic benefits.

As stated by researchers, “The unique structural attributes of benzodioxoles contribute significantly to their biological activity, making them targets for new drug discovery.” This highlights the significance of compounds like 7-methoxy-1,3-benzodioxole-5-carbaldehyde in the field of medicinal chemistry.

In summary, the study of 7-methoxy-1,3-benzodioxole-5-carbaldehyde opens doors to a deeper understanding of compound interactions and their potential usefulness in improving human health.

Synonyms
5780-07-4
1,3-Benzodioxole-5-carboxaldehyde, 7-methoxy-
Myristicinaldehyde
7-Methoxybenzo-1,3-dioxole-5-carboxaldehyde
DTXSID9064001
EINECS 227-304-8
AI3-24290
7-METHYOXY-1,3-BENZODIOXOLE-5-CARBOXALDEHYDE
DTXCID3042265
227-304-8
Myristicin aldehyde
5-methoxypiperonal
7-METHOXYBENZO[D][1,3]DIOXOLE-5-CARBALDEHYDE
3-Methoxy-4,5-methylenedioxybenzaldehyde
7-Methoxy-1,3-benzodioxole-5-carbaldehyde
7-Methoxy-benzo[1,3]dioxole-5-carbaldehyde
3-Methoxypiperonal
7-methoxy-2H-1,3-benzodioxole-5-carbaldehyde
7-methoxy-1,3-benzodioxole-5-carboxaldehyde
MFCD00016900
Myristicaldehyde
Myristicinaldehyd
3-Methoxy-4,5-(methylenedioxy)benzaldehyde
5NVX6YPV6E
myristicin aldehyde, AldrichCPR
SCHEMBL1418594
CHEMBL3577782
BBL027823
STK667579
3-Methoxypiperonal;Myristicin aldehyde
5-Formyl-7-methoxy-1,3-benzodioxole
AKOS000289320
FM70513
3-methoxy-4,5methylenedioxybenzaldehyde
NCGC00323064-01
AC-10297
AS-57202
DA-04718
SY122799
7-methoxy-1,3-dioxaindane-5-carbaldehyde
3,4-(Methylenedioxy)-5-methoxybenzaldehyde
DB-008316
CS-0036206
NS00046731
7-Methoxy-1,3-benzodioxole-5-carbaldehyde #
EN300-11058
Benzaldehyde, 3-methoxy-4,5-(methylenedioxy)-
7-methoxybenzo [d]1,3-dioxolane-5-carboaldehyde
7-Methoxybenzo[d][1,3]dioxole-5-carboxaldehyde
AB01318510-02
Z57032589