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Apigenin 7-methyl ether

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Identification
Molecular formula
C19H21NO4
CAS number
491-70-3
IUPAC name
7-methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one
State
State

The compound is in solid state at room temperature. It is typically available as a crystalline powder.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
527.55
Boiling point (Kelvin)
800.70
General information
Molecular weight
347.38g/mol
Molar mass
355.4080g/mol
Density
1.2650g/cm3
Appearence

It typically appears as a pale yellow or off-white crystalline powder.

Comment on solubility

Solubility of 7-methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one

The solubility of 7-methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one is influenced by several factors that are critical in determining its behavior in various solvents. This compound, with a complex molecular structure, presents unique characteristics:

  • Polarity: The presence of functional groups such as the morpholinomethyl moiety contributes to the overall polarity of the molecule, enhancing solubility in polar solvents like water.
  • Hydrophobic Interactions: Conversely, the chromenone scaffold and methyl groups may lead to increased hydrophobic interactions, suggesting limited solubility in non-polar solvents.
  • pH Dependency: The solubility may also vary with pH, particularly if the morpholine ring can participate in protonation, which might affect its interaction with solvents.

In summary, while 7-methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one shows promising solubility characteristics in polar solvents, the balance between its hydrophilic and hydrophobic parts means its solubility profile can vary significantly based on environmental conditions.

Interesting facts

Interesting Facts about 7-Methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one

This fascinating compound belongs to the class of chromones, a group of flavonoids that have attracted considerable attention in pharmacology due to their diverse biological activities. Here are some key points to consider:

  • Biological Activity: Chromones have been studied for their potential antioxidant, antimicrobial, and even anticancer properties. The specific modifications in this compound may enhance its therapeutic potential.
  • Morpholinomethyl Group: The addition of a morpholinomethyl substituent is particularly interesting as morpholine rings are known for their ability to improve solubility and bioavailability of drugs.
  • Natural Occurrence: Many chromones are derived from natural sources. Their presence in plants often links them to beneficial health effects traditionally attributed to herbal medicine.
  • Synthesis Techniques: This compound can be synthesized using various organic reactions, including multi-step synthetic routes that highlight the creativity and innovation within synthetic organic chemistry.

Overall, 7-methoxy-2,3-dimethyl-8-(morpholinomethyl)chromen-4-one stands as a testament to the interplay between natural products and modern chemical synthesis, paving the way for new therapeutic discoveries. As scientists delve deeper into its properties, this compound can reveal insights into future medicinal applications.
With its intriguing structure and potential applications, it continues to be a subject of interest in both academic and industrial settings.

Synonyms
3818-64-2
2,3-Dimethyl-7-methoxy-8-(morpholinomethyl)chromone
YM1JWR09WW
EINECS 223-309-4
NSC 169870
BRN 1084330
UNII-YM1JWR09WW
CHROMONE, 7-METHOXY-2,3-DIMETHYL-8-(MORPHOLINOMETHYL)-
NSC-169870
4H-1-Benzopyran-4-one, 7-methoxy-2,3-dimethyl-8-(4-morpholinylmethyl)-
DTXSID40191562
REC-7-0105
7-METHOXY-2,3-DIMETHYL-8-(4-MORPHOLINYLMETHYL)-4H-1-BENZOPYRAN-4-ONE
DTXCID80114053
4H-1-Benzopyran-4-one, 7-methoxy-2,3-dimethyl-8-(4-morpholinylmethyl)-(9CI)
223-309-4
REC 7-0105
7-Methoxy-2,3-dimethyl-8-(morpholinomethyl)-4H-chromen-4-one
7-methoxy-2,3-dimethyl-8-[(morpholin-4-yl)methyl]-4H-chromen-4-one
7-methoxy-2,3-dimethyl-8-(morpholin-4-ylmethyl)chromen-4-one
NSC169870
7-Methoxy-2,3-dimethyl-8-(morpholinomethyl)-4-benzopyrone
GJTMNUHTYIJXTJ-UHFFFAOYSA-N
Chromone,3-dimethyl-8-(morpholinomethyl)-
NS00030353
WLN: T66 BO EVJ C1 D1 IO1 J1- AT6N DOTJ
4H-1-Benzopyran-4-one,3-dimethyl-8-(4-morpholinylmethyl)-