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Dexchlorpheniramine

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Identification
Molecular formula
C26H30ClNO3S
CAS number
552-75-6
IUPAC name
7-methoxy-3-phenyl-4-[4-(2-pyrrolidin-1-ium-1-ylethoxy)phenyl]thiochroman-4-ol;chloride
State
State

At room temperature, dexchlorpheniramine chloride is in a crystalline solid state. It is stable under normal conditions but should be stored in a dry place to preserve its integrity.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.20
Boiling point (Celsius)
443.40
Boiling point (Kelvin)
716.50
General information
Molecular weight
390.96g/mol
Molar mass
390.9600g/mol
Density
1.2200g/cm3
Appearence

Dexchlorpheniramine is typically found as a white to off-white crystalline or powdery solid. It is largely soluble in water and tends to appear clear when dissolved, forming a homogeneous solution.

Comment on solubility

Solubility of 7-methoxy-3-phenyl-4-[4-(2-pyrrolidin-1-ium-1-ylethoxy)phenyl]thiochroman-4-ol;chloride

The solubility of 7-methoxy-3-phenyl-4-[4-(2-pyrrolidin-1-ium-1-ylethoxy)phenyl]thiochroman-4-ol;chloride can be influenced by various factors, including the presence of ionic and polar functional groups within its structure. Understanding its solubility characteristics is essential for applications in medicinal chemistry and pharmacology.

Factors Affecting Solubility:

  • Ionic Nature: The presence of the chloride ion can enhance water solubility, particularly in polar solvents.
  • Polar Groups: The methoxy and pyrrolidinium groups are polar, which may increase the compound's compatibility with polar solvents.
  • Size and Structure: The overall molecular structure, including its bulky phenyl rings, may limit solubility in non-polar solvents.
  • pH Levels: The solubility may vary with pH, particularly due to the potential ionization of the pyrrolidinium moiety.

In practical terms, this compound is likely to exhibit moderate to high solubility in polar solvents such as water, methanol, or ethanol. However, it may display reduced solubility in non-polar solvents due to steric hindrance and resultant hydrophobic interactions. Thus, it is crucial to consider the specific environment and solvent choice during experimental procedures and applications.

Interesting facts

Interesting Facts about 7-Methoxy-3-phenyl-4-[4-(2-pyrrolidin-1-ium-1-ylethoxy)phenyl]thiochroman-4-ol; Chloride

This fascinating compound offers a rich avenue of exploration in medicinal chemistry and pharmacology. Its unique molecular structure combines both a thiochroman core and a pyrrolidine moiety, which may provide significant biological activity. Here are some intriguing aspects about this compound:

  • Therapeutic Potential: Compounds similar to this one often investigate their anti-inflammatory, analgesic, and antitumor activities. Researchers are particularly keen on how the thiochroman component influences such biological effects.
  • Structural Complexity: The presence of multiple aromatic rings and functional groups enhances the compound's ability to interact with biological targets. This complexity could lead to interesting interactions within the body, making it a candidate for various pharmacological evaluations.
  • Pyrrolidine Influence: The inclusion of a pyrrolidine ring can contribute to the compound's activity profile. Pyrrolidines are known for exhibiting various pharmacological effects, including acting as neurotransmitter modulators.
  • Research Applications: This compound is not only important in theoretical chemistry but also holds promise for practical applications. For instance, it can serve as a lead compound for designing new drugs aimed at specific diseases or conditions.

As quoted in many research papers, "the combination of distinct functional groups can often produce synergistic effects that lead to enhanced therapeutic properties." Understanding the intricate relationships between molecular structure and biological activity is pivotal in the development of effective treatments.

In summary, the compound 7-methoxy-3-phenyl-4-[4-(2-pyrrolidin-1-ium-1-ylethoxy)phenyl]thiochroman-4-ol; chloride opens up numerous possibilities for scientific inquiry, showcasing the beauty and complexity of chemical compounds in the pharmaceutical landscape.

Synonyms
3,4-Dihydro-7-methoxy-3-phenyl-4-hydroxy-4-(p-(2-(1-pyrrolidyl)ethoxy)phenyl)-2H-1-benzothiapyran hydrochloride
16879-01-9
1XHI546Y1B
UNII-1XHI546Y1B
2H-1-Benzothiopyran-4-ol, 3,4-dihydro-7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, hydrochloride
Q27253071