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Coumarin 151

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Identification
Molecular formula
C15H11NO3
CAS number
120346-64-5
IUPAC name
7-methoxy-4-(4-pyridyl)chromen-2-one
State
State

The compound is in a solid state at room temperature, with a crystalline form that can vary from light orange to yellow.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
265.27g/mol
Molar mass
265.2720g/mol
Density
1.3320g/cm3
Appearence

The compound appears as a light orange to yellow crystalline powder. It may exhibit a subtle fluorescence under UV light due to its chromen-2-one structure.

Comment on solubility

Solubility of 7-methoxy-4-(4-pyridyl)chromen-2-one

The solubility of 7-methoxy-4-(4-pyridyl)chromen-2-one, a complex aromatic compound, is influenced by various factors including its structure and the presence of functional groups. This compound displays distinctive solubility characteristics, primarily due to its methoxy and pyridyl groups. Here are some key considerations regarding its solubility:

  • Polarity: The presence of the methoxy group contributes to the polarity of the molecule, which may enhance its solubility in polar solvents like methanol or ethanol.
  • Hydrogen Bonding: The pyridyl group can engage in hydrogen bonding, potentially increasing solubility in hydrogen-bonding solvents.
  • Aromatic Nature: The extensive conjugated system may result in limited solubility in nonpolar solvents due to its hydrophobic character.

In practical terms, it is often observed that:

  1. The compound is more soluble in polar solvents compared to nonpolar solvents.
  2. Inorganic salts may improve solubility when using specific co-solvents.
  3. Testing solubility in various mediums is essential to understand its practical applications.

In summary, while 7-methoxy-4-(4-pyridyl)chromen-2-one shows favorable solubility in specific environments, the exact solubility behavior can vary widely based on experimental conditions and the choice of solvent.

Interesting facts

Interesting Facts About 7-Methoxy-4-(4-pyridyl)chromen-2-one

7-Methoxy-4-(4-pyridyl)chromen-2-one is a fascinating compound that belongs to the class of flavonoids, a group of natural substances that have been known for their diverse biological activities. Here are some key points that highlight its significance:

  • Structure and Complexity: The compound features a chromen-2-one structure, which lends to its unique chemical behavior. The methoxy group attached to the chromen ring and the pyridyl substituent create a complex interplay of electron-donating and electron-withdrawing effects.
  • Biological Activity: This compound has attracted attention due to its potential antioxidant, anti-inflammatory, and antimicrobial properties. Research suggests that it may play a role in reducing oxidative stress, which is a contributing factor in many chronic diseases.
  • Synthetic Routes: The synthesis of 7-methoxy-4-(4-pyridyl)chromen-2-one can involve multiple steps, often requiring careful handling of reagents and conditions. Its study provides insights into synthetic organic chemistry and the design of novel compounds.
  • Applications in Medicine: Due to its favorable pharmacological properties, this compound is being explored for potential therapeutic applications. Its derivates could serve as lead compounds in drug development aimed at treating various health conditions.
  • Research Landscape: As the interest in natural compounds grows, the exploration of flavonoids like 7-methoxy-4-(4-pyridyl)chromen-2-one continues to expand, leading to new discoveries in both academic and pharmaceutical research.

In summary, 7-methoxy-4-(4-pyridyl)chromen-2-one represents an intriguing area of study where chemistry meets biology, underscoring the importance of interdisciplinary research in advancing our understanding of natural compounds and their applications in health and medicine.

Synonyms
841-97-4
COUMARIN, 7-METHOXY-4-(4-PYRIDYL)-
7-methoxy-4-(pyridin-4-yl)-2H-chromen-2-one
7-Methoxy-4-(4-pyridyl)coumarin
BRN 1078400
Coumarin deriv. 33
7-METHOXY-4-(PYRIDIN-4-YL)COUMARIN
BDBM9484
CHEMBL225156
DTXSID40232969