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Osthol

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Identification
Molecular formula
C15H16O3
CAS number
484-12-8
IUPAC name
7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
State
State

At room temperature, Osthol is solid. It is often found in its crystalline form, which makes it stable and easier to handle at ambient conditions.

Melting point (Celsius)
83.00
Melting point (Kelvin)
356.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
244.28g/mol
Molar mass
244.2790g/mol
Density
1.0960g/cm3
Appearence

Osthol appears as a colorless crystalline solid. It is known for its crystalline appearance and is often isolated in the form of fine, transparent needles.

Comment on solubility

Solubility of 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one

The solubility of the compound 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one can be influenced by several factors. Understanding these aspects often entails a nuanced look at its chemical structure and interactions with solvents.

Factors Affecting Solubility

  • Polarity: The presence of the methoxy group can influence the overall polarity of the molecule, potentially enhancing solubility in polar solvents.
  • Hydrophobic Interactions: The aliphatic group (3-methylbut-2-enyl) may impart hydrophobic characteristics that could limit solubility in water.
  • Hydrogen Bonding: Potential hydrogen bonding between the solute and solvent might enhance solubility in alcohols and other protic solvents.

Experiments generally show that compounds with similar functional groups can often dissolve in common organic solvents such as ethanol, methanol, and chloroform. However, less soluble in water due to the combined hydrophobic nature of parts of its structure. As a result, it's often necessary to consider specific solvent systems for effective dissolution.

In summary, the solubility of 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one is primarily tailored by its molecular characteristics and environmental conditions, making careful selection of solvents critical for practical applications.

Interesting facts

Interesting Facts about 7-Methoxy-8-(3-Methylbut-2-enyl)chromen-2-one

7-Methoxy-8-(3-methylbut-2-enyl)chromen-2-one is a fascinating compound that belongs to the flavonoid family. Flavonoids are renowned for their remarkable health benefits and are often found in fruits, vegetables, and beverages. Here are some intriguing aspects of this particular compound:

  • Structure & Characteristics: This compound features a chromenone structure, which is not only known for its unique aromatic properties but also plays a critical role in its biological activities. The presence of a methoxy group and an alkenyl side chain contributes to its distinct chemical behavior.
  • Natural Occurrence: Compounds similar to 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one can be found in various plants. They serve vital roles, ranging from pigmentation to UV protection.
  • Potential Health Benefits: Research has suggested that flavonoids possess antioxidant, anti-inflammatory, and anti-cancer properties. While studies are ongoing regarding this specific compound, related flavonoids have illustrated these beneficial effects.
  • Cultural Significance: Many plants producing flavonoids, including compounds like this one, are often used in traditional medicine around the world. They have been historically linked to various health remedies.
  • Aromatic Profile: The compound may have unique aromatic qualities, likely contributing to fragrances in herbal teas and essential oils, enhancing scents in natural products.

As a science student or an enthusiast, understanding compounds like 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one opens the door to not just grasping their chemical properties but also appreciating their larger ecological and health roles. Whether it's through research or practical application, the exploration of such compounds can lead to significant discoveries in both the laboratory and the realm of wellness.

Synonyms
Osthole
Osthol
484-12-8
Ostole
Ostol
7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-
7-Methoxy-8-isopentenylcoumarin
8-(3-Methyl-2-butenyl)herniarin
NSC 31868
UNII-XH1TI1759C
Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-
XH1TI1759C
NSC-31868
HSDB 8479
7-methoxy-8-(3-methyl-2-butenyl)-2h-1-benzopyran-2-one
7-METHOXY-8-(3-METHYLBUT-2-ENYL)-2-CHROMENONE
7-methoxy-8-(3-methylpent-2-enyl)coumarin
7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one
7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
7-methoxy-8-(3-methyl-2-butenyl)coumarin
7-METHOXY-8-(3-METHYL-2-BUTENYL)-COUMARIN
MFCD00076049
CHEMBL52229
CHEBI:69832
NSC31868
SMR000156202
Osthole (Osthol)
A0O
7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one
Osthole (Standard)
Spectrum_001542
SpecPlus_000946
OSTHOLE [MI]
Spectrum2_000723
Spectrum3_001645
Spectrum4_001687
Spectrum5_000334
Osthole, analytical standard
Oprea1_642606
Oprea1_873803
SCHEMBL50436
BSPBio_003369
KBioGR_001954
KBioSS_002022
MLS000574904
MLS001048988
MLS006011425
DivK1c_007042
SPECTRUM1504165
SPBio_000646
MEGxp0_000155
ACon1_002155
GTPL10302
HY-N0054R
KBio1_001986
KBio2_002022
KBio2_004590
KBio2_007158
KBio3_002589
DTXSID20197507
HMS2267O21
HMS3656A07
BCP10832
HY-N0054
BBL013019
BDBM50240512
CCG-40172
MSK156874
s2337
STK396321
AKOS000277663
AC-8041
DS-0881
FO09975
SDCCGMLS-0066780.P001
NCGC00095694-01
NCGC00095694-02
NCGC00095694-03
NCGC00095694-05
NCGC00095694-06
WLN: T66 BOVJ IO1 J2UY1&1
NS00031794
O0426
SW219438-1
C09280
AM-721/20651007
Osthole, primary pharmaceutical reference standard
SR-01000721624
Q4338679
SR-01000721624-4
BRD-K78294846-001-03-3
BRD-K78294846-001-12-4
7-Methoxy-8-(3-methyl-2-butenyl)-2H-chromen-2-one #
Osthole, European Pharmacopoeia (EP) Reference Standard
7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-2-one
7-Methoxy-8-(3-methyl-2-butenyl)coumarin;7-Methoxy-8-isopentenylcoumarin;Osthol
1440642-68-1
InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H