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Berberine

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Identification
Molecular formula
C20H22NO4
CAS number
2086-83-1
IUPAC name
7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline
State
State

At room temperature, berberine is generally found in a solid state.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
336.42g/mol
Molar mass
336.4180g/mol
Density
1.3200g/cm3
Appearence

Berberine is typically a yellow crystalline solid.

Comment on solubility

Solubility of 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline

The solubility characteristics of 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline can be quite intriguing due to its complex structure. Understanding its solubility involves considering several factors:

  • Polarity: The presence of multiple functional groups can influence the overall polarity of the compound, which in turn affects its solubility in various solvents.
  • Solvent Compatibility: This compound may have varying solubility in polar versus non-polar solvents. For example, it may dissolve better in organic solvents such as dichloromethane or ethanol compared to water.
  • Temperature Effects: Solubility can also be temperature-dependent. Higher temperatures may enhance solubility, especially in organic solvents.

In summary, the solubility of 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline is influenced by its structural characteristics and the nature of the solvent used. As stated, it's essential to perform empirical tests to ascertain specific solubility values for practical applications, keeping in mind that “the solubility of a compound is a key to its chemical reactivity and biological activity.”

Interesting facts

Interesting Facts about 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline

7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline is a fascinating compound with unique structural and functional characteristics. Its complex molecular architecture makes it a significant subject of study in organic chemistry and medicinal research.

Structural Features

  • Isoquinoline Core: The compound features an isoquinoline core, which is important in the development of various therapeutic agents.
  • Dioxolo Ring System: The presence of the dioxolo ring contributes to the compound's chemical reactivity and potential applications.
  • Methylcyclohexyl Substitution: The incorporation of a methylcyclohexyl group enhances lipophilicity, which may be critical for its biological activity.

Potential Applications

  • Pharmaceutical Research: Compounds with isoquinoline structures are often studied for their pharmacological properties, including anti-cancer and anti-inflammatory effects.
  • Research in Material Science: Such compounds may also find utility in the development of advanced materials due to their unique electronic properties.
  • Natural Product Synthesis: The complex structure inspires synthetic chemists to develop new methodologies for constructing challenging molecular architectures.

As with many organic compounds, the study of 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline invites chemists to explore its potential therapeutic effects and to better understand its mechanisms. Researchers often quote that "the structure of a compound is a story waiting to be uncovered," making this compound a promising candidate for further exploration.

In summary, 7-methyl-5-[(1-methylcyclohexyl)methyl]-[1,3]dioxolo[4,5-g]isoquinoline exemplifies the interplay between synthetic complexity and biological potential, demonstrating the importance of chemical diversity in advancing our understanding of molecular functions.