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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
632-89-9
IUPAC name
7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

At room temperature, berberine chloride is a solid.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
408.00
Boiling point (Kelvin)
681.15
General information
Molecular weight
372.82g/mol
Molar mass
372.8200g/mol
Density
1.3800g/cm3
Appearence

Berberine chloride appears as a yellow crystalline powder. It is noted for its vibrant color, which is characteristic of many berberine compounds.

Comment on solubility

Solubility of 7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The solubility of 7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is an intriguing topic due to its unique molecular structure. This compound features a positively charged isoquinoline moiety, which affects its interactions with solvents.

Here are some key points regarding its solubility:

  • Polar Solvents: The presence of the dioxolo group and the ionic chloride moiety suggests that this compound may exhibit significant solubility in polar solvents such as water and alcohols.
  • Non-Polar Solvents: Conversely, its bulky cyclopentyl group may lead to lower solubility in non-polar solvents due to hydrophobic interactions.
  • Temperature Effects: As with many ionic compounds, increased temperature might enhance solubility, allowing for greater dissolution in aqueous solutions.

Understanding the solubility behavior of this compound is crucial for its applications in various fields, including pharmaceuticals and organic synthesis. The interaction between its ionic and non-polar characteristics indicates a complex solubility profile that warrants further investigation.

Interesting facts

Exploring 7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The compound known as 7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride belongs to a fascinating class of organic compounds that showcase the intricate relationships between molecular structure and biological activity. This particular compound is notable for its complex structure, featuring a fused dioxole and isoquinoline structure, which are pivotal in many pharmacological applications.

Key Characteristics

  • Structural Complexity: The compound's distinct arrangement allows it to engage with biological systems in unique ways, potentially influencing various biochemical pathways.
  • Pharmacological Potential: Compounds like this are being researched for their potential therapeutic effects, including anti-inflammatory and analgesic properties.
  • Versatile Synthesis: The synthetic routes to create this compound can involve multiple steps, often utilizing various organic chemistry techniques, highlighting its significance in synthetic organic chemistry.
  • Interdisciplinary Impact: Its studies do not only focus on chemistry but also bridge into fields such as medicinal chemistry and pharmacology, demonstrating the compound's broad relevance.

A notable aspect of this compound is its potential for use in drug development. As scientists continue to uncover the mechanism of action behind isoquinoline derivatives, there could be promising advancements in creating new therapeutic agents. As one researcher aptly put it, "Understanding the structure-function relationship in these compounds is crucial for harnessing their full therapeutic potential."

Engaging with compounds like 7-methyl-5-[(1-methylcyclopentyl)methyl]-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride not only fosters a deeper understanding of chemical reactivity but also paves the way for innovations in health and medicine.

Synonyms
1,3-Dioxolo(4,5-g)isoquinoline, 7-methyl-5-((1-methylcyclopentyl)methyl)-, hydrochloride
16994-50-6
7-Methyl-5-((1-methylcyclopentyl)methyl)-1,3-dioxolo(4,5-g)isoquinoline hydrochloride