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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
632-97-9
IUPAC name
7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

At room temperature, berberine chloride exists as a solid in the form of yellow crystals. It is known for its use in traditional medicine and modern pharmacology.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
371.82g/mol
Molar mass
371.8200g/mol
Density
1.3305g/cm3
Appearence

Berberine chloride appears as a yellow crystalline powder. It is often used in its hydrated form and can be found in various plant species. The compound exhibits a vibrant yellow color which is visually distinctive.

Comment on solubility

Solubility of 7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The solubility of 7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride exhibits interesting characteristics due to its ionic nature and complex structure. Key factors that influence its solubility include:

  • Ionicity: As a quaternary ammonium compound, this chloride salt is likely to be soluble in polar solvents such as water owing to the presence of the ionic Cl- component.
  • Hydrophobic Interactions: The large hydrophobic rear structure provided by the 2-methylbutyl group may lead to reduced solubility in pure water, but it could increase solubility in organic solvents.
  • pH Dependence: The solubility may vary with changes in pH, potentially affecting the ionization of the compound in solution.

Overall, it can be suggested that while 7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride has a strong likelihood of dissolving in polar solvents, the efficiency of solubility will be greatly influenced by the solvent choice and environmental conditions.

Interesting facts

Exploring 7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

This unique compound, with its intricate structure, is part of the isoquinoline family, renowned for its diverse biological activities and applications. Here are some fascinating insights:

  • Structure and Complexity: The molecule contains a dioxole ring fused with an isoquinoline skeleton, which contributes to its potential reactivity and interactions with biological targets.
  • Biological Importance: Isoquinolines are often studied for their pharmacological properties, including their roles in medicinal chemistry, as some derivatives exhibit anti-cancer and anti-inflammatory activities.
  • Potential Applications: Compounds like this one are investigated for their potential use in developing new therapeutic agents, enhancing drug delivery systems, and even in materials science.
  • Chiral Centers: The presence of multiple chiral centers in this compound introduces an element of stereochemistry that could significantly influence its biological activity and pharmacodynamics.
  • Research Interest: Given its complex structure, this compound is likely a subject of ongoing research, potentially leading to significant discoveries in the field of organic chemistry.

In summary, the 7-methyl-5-(2-methylbutyl)-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride compound stands as a testament to the rich interplay between structure and function in chemical compounds. As we continue to unravel the mysteries behind such complex molecules, the implications for drug discovery and organic synthesis are boundless.

Synonyms
17105-22-5
1-(2-Methylbutyl)-3-methyl-6,7-methylenedioxyisoquinoline hydrochloride
7-Methyl-5-(2-methylbutyl)-1,3-dioxolo(4,5-g)isoquinoline hydrochloride
1,3-DIOXOLO(4,5-g)ISOQUINOLINE, 7-METHYL-5-(2-METHYLBUTYL)-, HYDROCHLORIDE