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Melatonin

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Identification
Molecular formula
C13H16N2O
CAS number
73-31-4
IUPAC name
(7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol
State
State

At room temperature, Melatonin is typically a solid.

Melting point (Celsius)
117.50
Melting point (Kelvin)
390.65
Boiling point (Celsius)
541.30
Boiling point (Kelvin)
814.45
General information
Molecular weight
174.25g/mol
Molar mass
174.2450g/mol
Density
1.1200g/cm3
Appearence

The compound typically appears as white crystals or powder.

Comment on solubility

Solubility of (7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol

The solubility of (7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol is influenced by its complex structure, which incorporates both indole and quinoline functionalities. As a rule of thumb:

  • Polarity: This compound exhibits significant polar characteristics due to the presence of a hydroxymethyl (-CH2-OH) group, which tends to enhance solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in alcohols and dimethyl sulfoxide (DMSO), while exhibiting lower solubility in non-polar solvents such as hexane and benzene.
  • Hydrogen Bonding: The hydroxymethyl group allows the compound to engage in hydrogen bonding, which can improve solubility in aqueous environments under certain conditions.

However, due to its aromatic nature and multi-ring structure, solubility can be affected by various factors including temperature and the presence of other solutes. As is often noted, “solubility is key to understanding chemical behavior,” underpinning its critical role in both practical applications and theoretical studies.

To sum up, while (7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol shows promise for solubility in polar solvents, definitive behavior will depend on a variety of environmental conditions and solvent interactions.

Interesting facts

Interesting Facts about (7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol

This fascinating compound stands out in the realm of organic chemistry due to its unique structure and potential applications. Its complex molecular architecture, characterized by an indole and quinoline framework, highlights the interplay between various heterocyclic compounds. Here are some noteworthy aspects:

1. Structural Features

  • Indole and Quinoline Fusion: The compound features a robust fusion of the indole and quinoline rings, leading to enriched biological properties.
  • Methyl Substituent: The presence of a methyl group at position 7 can significantly influence the compound's reactivity and interactions with biological systems.

2. Biological Relevance

Compounds with similar structures have garnered attention in medicinal chemistry:

  • Potential Anticancer Activity: Many indole alkaloids exhibit potential anticancer properties, making this compound a subject of interest for further research.
  • Neuroprotective Effects: Some derivatives of indole and quinoline have shown promise in neuroprotection, opening doors for investigating cognitive health interventions.

3. Synthetic Pathways

The synthesis of this compound can be quite intricate and may involve:

  • The use of various catalytic and non-catalytic methods to form the fused ring system.
  • Careful control of reaction conditions to ensure the stability of the resulting product.

4. Future Perspectives

With ongoing research into its properties:

  • Drug Development: This compound may serve as a lead compound or precursor in developing novel pharmaceuticals.
  • Material Science: The unique properties of this compound might find utility in advanced materials or nanotechnology.

In conclusion, (7-methyl-6,6a,8,10a-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl)methanol represents a captivating subject for chemists, blending intricate structural design with a promising biological profile. As we continue to explore the potential of such compounds, their pathways to diverse applications become clearer, underscoring the dynamic nature of chemical research.

Synonyms
Elymoclavin
NSC109431
Ergoline-8-methanol,9-didehydro-6-methyl-
(6-Methyl-8,9-didehydroergolin-8-yl)methanol #