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Celiprolol

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Identification
Molecular formula
C20H27N3O3
CAS number
56865-91-3
IUPAC name
7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
State
State

The compound is in a solid state at room temperature.

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
373.47g/mol
Molar mass
373.4670g/mol
Density
1.2480g/cm3
Appearence

Celiprolol typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

The solubility of 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide presents intriguing characteristics that are essential for various applications in pharmaceuticals and chemical research.

Generally, the solubility profile of this compound can be influenced by several factors, including:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents such as water.
  • pH Levels: The solubility may vary significantly with changes in pH, as carboxamide groups can undergo protonation or deprotonation.
  • Temperature: Increasing temperature often increases solubility, but the effect can vary depending on the specific interactions within the compound.
  • Solvent Type: Compatibility with different solvents can lead to different solubility outcomes; for instance, organic solvents might dissolve the compound more effectively than water.

It is often said that "like dissolves like," meaning that non-polar compounds are better dissolved in non-polar solvents. As a result, the solubility of this compound may be higher in organic solvents. However, it may face challenges when interacting with polar solvents.

In conclusion, understanding the solubility of 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide requires careful consideration of its chemical structure, environmental conditions, and the nature of the solvents in use. This complexity is what makes the study of solubility both challenging and fascinating in the field of chemistry.

Interesting facts

Interesting Facts about 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

The compound known as 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide belongs to a fascinating class of organic compounds that has garnered attention in various fields, particularly in medicinal chemistry.

Structural Insights

This compound features a unique indoloquinoline structure, which is notable for its complex ring systems. Some interesting points about its structure include:

  • Indole and Quinoline Fusion: The compound showcases a hybrid of indole and quinoline, which can significantly influence its biological activity.
  • Methyl Substitution: The presence of a methyl group at the position 7 enhances its lipophilicity, potentially affecting its interaction with biological membranes.
  • Carboxamide Group: The carboxamide functional group can facilitate hydrogen bonding, playing a critical role in the compound's interactions with target proteins.

Biological Significance

Researchers are intrigued by the potential applications of this compound. Noteworthy aspects include:

  • Pharmacological Activity: Several derivatives of quinoline are known to exhibit a broad range of activities, including antibacterial, antiviral, and anticancer properties.
  • Research Applications: Compounds of this class are often used as lead compounds in drug design, driving innovative research in pharmacology.
  • Receptor Binding: Indoloquinolines may interact with various receptors or enzymes, which highlights the importance of studying their structure-activity relationships.

Conclusion

In summary, 7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide is a compelling compound in the realm of chemical research. Its intricate structure and potential biological activities continue to inspire scientists in the quest for novel therapeutics. As Dr. Marie Curie once said, "Nothing in life is to be feared, it is only to be understood." This compound exemplifies the complex relationship between molecular structure and biological function.

Synonyms
6-Methyl-9,10-didehydroergoline-8-carboxamide
7-methyl-6,6a,8,9-tetrahydro-4H-indolo(4,3-fg)quinoline-9-carboxamide
7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Ergoline-8-carboxamide, 9,10-didehydro-6-methyl-, (8.beta.)-
Lysergic amide
Ololiuqui (Salt/Mix)
SCHEMBL26265228
DTXSID30861989
GENAHGKEFJLNJB-UHFFFAOYSA-N
NS00134356
6-Methyl-9,10-didehydroergoline-8.beta.-carboxamide #
9,10-Didehydro-6-methyl-ergoline-8-.beta.-carboxamide
Ergoline-8.beta.-carboxamide, 9,10-didehydro-6-methyl-