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7-Methylcoumarin

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Identification
Molecular formula
C10H8O2
CAS number
2445-83-2
IUPAC name
7-methylchromen-2-one
State
State

At room temperature, 7-Methylcoumarin is typically in a solid state.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.15
General information
Molecular weight
160.17g/mol
Molar mass
160.1680g/mol
Density
1.1977g/cm3
Appearence

7-Methylcoumarin appears as a crystalline solid that can vary in color, usually presenting as white to slightly yellow. It can also exhibit a slight fluorescence under UV light due to its conjugated chromophore structure.

Comment on solubility

Solubility of 7-methylchromen-2-one

The solubility of 7-methylchromen-2-one, also known as 7-methylcoumarin, is quite intriguing and can be influenced by several factors. This compound is characterized by its unique structure that can affect its interactions with solvents.

Key Points About Solubility:

  • Polarity: Due to the presence of a carbonyl group within the chromenone structure, 7-methylchromen-2-one tends to exhibit moderate polarity, which allows it to dissolve in polar solvents to an extent.
  • Solvents: It is generally soluble in organic solvents such as ethanol, methanol, and acetone, but has limited solubility in water. This is typical for many derivatives of coumarin.
  • pH Influence: The solubility can also be affected by the pH of the environment. In acidic conditions, the solubility may increase due to potential protonation of the carbonyl group.
  • Temperature: As with many organic compounds, the solubility of 7-methylchromen-2-one typically increases with an increase in temperature.

In essence, while 7-methylchromen-2-one can dissolve in various organic solvents, its overall solubility in aqueous environments remains limited. Understanding these properties is essential for its applications in different chemical contexts.

Interesting facts

Interesting Facts about 7-Methylchromen-2-one

7-Methylchromen-2-one, also known as 7-methylcoumarin, is a fascinating compound that belongs to the coumarin family. This aromatic organic compound is characterized by its unique fused ring structure and contributes to various fields of study, including medicinal chemistry and natural product research. Here are some intriguing aspects of this compound:

  • Natural Occurrence: 7-Methylchromen-2-one can be found in several plants, particularly in the Asteraceae family, showcasing its potential as a natural product with applications in flavoring and fragrance.
  • Biological Activity: The compound exhibits remarkable biological activities, including antimicrobial, antioxidant, and anti-inflammatory properties, making it a subject of extensive research in pharmacology.
  • Fluorescence Properties: 7-Methylchromen-2-one displays unique fluorescence characteristics, which are utilized in various analytical applications, such as fluorescence spectroscopy.
  • Synthesis: This compound can be synthesized through several methods, including the Pechmann condensation and photochemical reactions, providing a rich topic for synthetic chemistry enthusiasts.
  • Applications: The potential applications of 7-Methylchromen-2-one extend beyond natural products. It is used as a building block in the synthesis of various bioactive molecules, highlighting its versatility in drug development.

In conclusion, 7-Methylchromen-2-one is not only significant for its chemical structure but also for its wide array of biological and practical applications. Its study opens doors to both academic research and industrial potentials, making it a truly remarkable compound in the realm of chemistry.

Synonyms
7-Methylcoumarin
7-Methyl-2H-chromen-2-one
7-methylchromen-2-one
2H-1-Benzopyran-2-one, 7-methyl-
7-Methyl coumarin
COUMARIN, 7-METHYL-
7-Methyl-2H-1-benzopyran-2-one
UNII-YCN83T03QU
EINECS 219-499-3
YCN83T03QU
NSC 19511
BRN 0122625
NSC-19511
DTXSID0062424
5-17-10-00169 (Beilstein Handbook Reference)
DTXCID4037083
219-499-3
dlhxrduxnveiey-uhfffaoysa-n
2445-83-2
7-Methylcumarin
7-Methyl-Coumarin
7-Methyl-chromen-2-one
MFCD00006880
NSC19511
7-Methylcoumarin (Standard)
SCHEMBL76393
7-Methylcoumarin, >=98%
CHEMBL346541
7-Methyl-2H-chromen-2-one #
HY-N5092R
CHEBI:166605
HY-N5092
7-Methylcoumarin, analytical standard
AKOS015842507
FM71675
NCI60_001631
PD158960
SY051344
TS-02124
DB-046453
CS-0032411
M1236
NS00027665
EN300-98011
P50004
7-Methylcoumarin 100 microg/mL in Acetonitrile
Q27294453