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7-Nitroindole

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Identification
Molecular formula
C8H6N2O2
CAS number
6160-13-2
IUPAC name
7-nitro-1H-indole
State
State

This compound is generally a solid under room temperature conditions, typically forming yellow crystals.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
176.15g/mol
Molar mass
176.1570g/mol
Density
1.3960g/cm3
Appearence

7-Nitroindole typically appears as a yellow crystalline solid. The compound may have a distinctive odor depending on its purity and presence of impurities. The crystals could vary in size from small fine crystals to larger, more coarse aggregates.

Comment on solubility

Solubility of 7-nitro-1H-indole

7-nitro-1H-indole, also referred to as 7-nitroindole, exhibits specific solubility characteristics that are important for its application in various chemical processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: 7-nitro-1H-indole is generally more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), making it suitable for use in organic synthesis and biochemical applications.
  • Hydrophobic Nature: Its structure contributes to its hydrophobic nature, resulting in limited solubility in polar solvents like water. This characteristic can affect its dissolution and bioavailability in aqueous environments.
  • Effect of Temperature: Like many organic compounds, the solubility of 7-nitro-1H-indole may increase with temperature, which can be a crucial factor when preparing solutions for experiments.
  • pH Considerations: The solubility can also be influenced by the pH of the solution due to the presence of acidic or basic functional groups that may interact with the solvent.

In summary, while 7-nitro-1H-indole is soluble in organic solvents, its low solubility in water should be taken into consideration in practical applications. Understanding these solubility aspects is crucial for researchers working with this compound, ensuring effective use in various chemical contexts.

Interesting facts

Interesting Facts About 7-Nitro-1H-Indole

7-Nitro-1H-indole is a fascinating compound that has attracted significant attention in both chemical and biological fields. This compound is characterized by a bicyclic structure, which is integral to its unique properties and applications.

Biological Significance

One of the most notable aspects of 7-nitro-1H-indole is its role in medicinal chemistry:

  • It has been studied for its potential as an antimicrobial agent, showcasing efficacy against a variety of pathogenic microorganisms.
  • This compound exhibits interesting anti-inflammatory properties, contributing to ongoing research in therapeutic applications.
  • 7-Nitro-1H-indole also plays a part in the study of neurotransmitter systems, with implications for understanding certain neurological diseases.

Synthetic Applications

The significance of 7-nitro-1H-indole extends into synthetic chemistry as well:

  • It serves as a valuable building block for synthesizing more complex organic molecules, aiding in pharmaceutical development.
  • This compound can be used in the creation of fluorescent probes, which are essential for numerous scientific applications, including bioimaging.
  • Its versatile reactivity can lead to diverse derivatives that exhibit unique properties and functionalities.

Environmental Impact

In recent studies, the environmental implications of 7-nitro-1H-indole have been explored:

  • This compound's impact on ecosystems is being assessed, particularly in aquatic environments, where its presence might influence biochemical processes.
  • Research is being conducted to evaluate its role in the biodegradation process and how it may potentially affect bioremediation strategies.

In conclusion, 7-nitro-1H-indole is not just a simple molecule; it embodies a wealth of scientific opportunity. With its diverse applications in medicine, synthetic chemistry, and environmental science, it continues to inspire research and innovation in numerous domains. As chemistry students or scientists, exploring the capabilities of such compounds opens doors to novel discoveries and applications that can significantly impact society.

Synonyms
7-Nitroindole
6960-42-5
INDOLE, 7-NITRO-
NSC 69874
BRN 0130874
DTXSID20219879
5-20-07-00044 (Beilstein Handbook Reference)
DTXCID20142370
677-504-8
lzjgqivwukftrd-uhfffaoysa-n
7-Nitro-1H-indole
1H-Indole, 7-nitro-
MFCD00005683
7-nitro indole
NSC69874
7-Nitroindole, 97%
SCHEMBL259909
CHEMBL164632
NSC-69874
STK249657
AKOS005207160
AB00500
AC-3141
CS-W001974
FN02020
HY-W001974
PS-5704
SY004017
DB-012440
N0685
EN300-118948
Z1255382963