7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine

Identification

Molecular formula

C₁₆H₁₅N₃O₃

CAS number

162529-56-0

IUPAC name

7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine

State

The compound is typically in a solid state at room temperature.

Melting point (Celsius)

184.00

Melting point (Kelvin)

457.00

Boiling point (Celsius)

455.00

Boiling point (Kelvin)

728.00

General information

Molecular weight

300.31g/mol

Molar mass

358.3560g/mol

Density

1.4000g/cm³

Appearence

The compound is typically in a crystalline solid form, with possible color variations depending on its purity and specific structural form.

Comment on solubility

Solubility of 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine

The solubility of 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine can be influenced by various factors due to its complex structure. Here are some critical aspects to consider:

Polarity: The presence of both nitro and pyridine groups can enhance the compound's polarity, increasing the likelihood of dissolving in polar solvents like water.
Solvent Dependence: This compound may show different solubility profiles in various solvents. For example:
- Highly polar solvents (e.g., methanol, ethanol) may promote better solubility.
- Non-polar solvents (e.g., hexane, chloroform) might exhibit poor solubility.
Temperature Effects: Generally, an increase in temperature can lead to greater solubility for many organic compounds, including this particular one.
pH Influence: The solubility may also be affected by the pH of the solution, especially because of the nitrogen in the pyridine group which could participate in protonation or deprotonation reactions.

In conclusion, understanding the solubility of 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine requires careful consideration of its molecular structure and the solvent environment, which can significantly alter its behavior in solution. As highlighted, factors like polarity, solvent type, temperature, and pH play critical roles in determining how well this compound will dissolve in various mediums.

Interesting facts

Interesting Facts about 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine

The compound 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine is a fascinating member of the benzoxazine family, known for its unique structure and diverse chemical properties. Here are some key points to consider:

Pharmacological Potential: Benzoxazines, including this compound, are being investigated for their potential biological activities. Certain derivatives have shown promise as anti-cancer agents and can act on various biochemical pathways.
Structural Features: The presence of the nitro group and the pyridyl moiety in its structure gives this compound intriguing characteristics that can influence its reactivity and interaction with biological systems.
Research Applications: Compounds like this are often used in the synthesis of more complex molecules in medicinal chemistry, providing a scaffold for the design of new drugs.
Versatility: The benzoxazine nucleus is versatile and can undergo several types of chemical reactions, making it an attractive target for various synthetic applications.
Material Science: Beyond medicinal chemistry, benzoxazines are studied for their potential application in polymer science, where they can serve as precursors to useful materials.

"The study of such compounds is crucial as they often bridge the gap between synthetic chemistry and biological activity."

In conclusion, 7-nitro-3-[2-(4-pyridyl)ethyl]-1,4-dihydro-2,3-benzoxazine exemplifies the intersection of structure and function, promising ample opportunities for both research and application in various fields of science.