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(7-nitro-8-quinolyl) 2-benzylidenebutanoate

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Identification
Molecular formula
C20H16N2O4
CAS number
223692-47-3
IUPAC name
(7-nitro-8-quinolyl) 2-benzylidenebutanoate
State
State

At room temperature, (7-nitro-8-quinolyl) 2-benzylidenebutanoate is typically in a solid state. It is generally stable under standard laboratory conditions.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
637.00
Boiling point (Kelvin)
910.15
General information
Molecular weight
344.34g/mol
Molar mass
344.3420g/mol
Density
1.3162g/cm3
Appearence

The compound (7-nitro-8-quinolyl) 2-benzylidenebutanoate typically presents as a crystalline solid. The exact color and shape of the crystals may vary based on the method of synthesis and purification, but it generally appears as a pale yellow to light beige material. Its appearance is influenced by the presence of the nitro group, which often imparts a yellow hue to organic compounds.

Comment on solubility

Solubility of (7-nitro-8-quinolyl) 2-benzylidenebutanoate

(7-nitro-8-quinolyl) 2-benzylidenebutanoate is a complex organic compound, and its solubility can be influenced by several factors. This compound is generally characterized by its relatively low solubility in water but shows a higher affinity for organic solvents. Here are some key points regarding its solubility:

  • Solvent Polarity: The solubility of this compound increases with the decreasing polarity of the solvent. It is most soluble in organic solvents such as methanol, ethanol, and dichloromethane.
  • Temperature Effects: Higher temperatures tend to enhance the solubility of (7-nitro-8-quinolyl) 2-benzylidenebutanoate in organic solvents, as molecular motions increase, allowing for better interaction between solute and solvent.
  • Hydrogen Bonding: The presence of nitro and quinoline groups in the structure can lead to various intermolecular interactions, impacting solubility in polar solvents to some extent.

It is important to note that while this compound is not soluble in water, its solubility in organic solvents makes it suitable for applications in organic synthesis and pharmaceutical formulations. Understanding these solubility parameters is crucial for effective utilization in laboratory settings.

Interesting facts

Interesting Facts about (7-nitro-8-quinolyl) 2-benzylidenebutanoate

(7-nitro-8-quinolyl) 2-benzylidenebutanoate is a fascinating compound, not just for its unique structure but also for its broad range of applications in various fields. Here are some compelling aspects to consider:

  • Bioactivity: This compound exhibits remarkable bioactive properties, particularly in the field of medicinal chemistry. It has been studied for its potential use as an antimicrobial and anticancer agent, making it a subject of interest for pharmaceutical research.
  • Chemical versatility: The presence of the quinoline motif allows for multiple derivatization pathways, which enables scientists to synthesize various analogs with potentially enhanced properties. This versatility is crucial for drug design and development.
  • Research significance: The structure contains both nitro and quinoline groups, which are known for their influence in binding interactions. Researchers are exploring how such compounds can serve as chelators in coordination chemistry, enhancing their utility in materials science.
  • Mechanistic studies: Studies on this compound can provide insights into the mechanism of action of similar compounds by assessing their reactivity and interaction with biological targets, thus contributing to the understanding of drug pathways.
  • Synthetic challenge: The synthesis of (7-nitro-8-quinolyl) 2-benzylidenebutanoate can be challenging due to the need for specific conditions to maintain the integrity of functional groups. This makes it a significant rehearsal for students and chemists alike striving to master organic synthesis techniques.

In summary, (7-nitro-8-quinolyl) 2-benzylidenebutanoate serves as an elegant example of how structural characteristics in organic compounds correlate with functional properties. Its continued study not only promises advancements in pharmacology but also fuels educational conversations in organic chemistry, bridging the gap between theoretical knowledge and practical application. As the famous chemist Linus Pauling once stated, "The best way to have a good idea is to have a lot of ideas." The exploration of compounds like this opens a gateway to innovative research and discovery.