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(7-nitro-8-quinolyl) 2,4-dimethoxybenzoate

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Identification
Molecular formula
C18H14N2O6
CAS number
402915-85-3
IUPAC name
(7-nitro-8-quinolyl) 2,4-dimethoxybenzoate
State
State
At room temperature, (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate is typically found in a solid state.
Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
352.34g/mol
Molar mass
352.3350g/mol
Density
1.3450g/cm3
Appearence

(7-nitro-8-quinolyl) 2,4-dimethoxybenzoate typically appears as a crystalline solid with a color that can range from pale yellow to an off-white shade. Its appearance is consistent with many aromatic compounds that have extended conjugated systems.

Comment on solubility

Solubility of (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate

(7-nitro-8-quinolyl) 2,4-dimethoxybenzoate, known for its intriguing structure, presents interesting solubility characteristics. Understanding its solubility can provide insights into its behavior in various solvents and applications.

Solubility Characteristics

In general, the solubility of this compound is influenced by several factors:

  • Polarity: The presence of polar functional groups, such as methoxy groups and a nitro substituent, suggests that the compound may exhibit moderate solubility in polar solvents like methanol and ethanol.
  • Nonpolar Solvents: Conversely, the aromatic nature of the quinoline structure may lead to enhanced solubility in nonpolar solvents like chloroform or dichloromethane.
  • Temperature Influence: Increased temperature can aid in enhancing solubility, making it more soluble in organic solvents at elevated temperatures.

It is often stated that “like dissolves like,” meaning:

  • Polar solvents dissolve polar solutes.
  • Nonpolar solvents dissolve nonpolar solutes.

Empirical studies indicate that this compound’s solubility may vary significantly based on the chosen solvent and its concentration. It is essential to conduct solubility tests in different media to determine its effective usage in drug formulations or other chemical processes.
Additionally, alterations in pH could also affect solubility due to the compound’s functional groups. Therefore, a thorough understanding of these interactions is crucial in predicting and harnessing its solubility behavior effectively.

Interesting facts

Interesting Facts about (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate

(7-nitro-8-quinolyl) 2,4-dimethoxybenzoate is a fascinating compound, especially significant in the realm of medicinal chemistry and material science. Here are some intriguing aspects:

  • Biomedical Applications: This compound has been researched for its potential pharmacological properties, particularly in the development of drugs targeting various biological pathways. Its structure suggests potential interactions within biological systems, making it a candidate for further study in pharmacokinetics.
  • Fluorescent Properties: The quinoline moiety present in the compound endows it with unique photophysical properties. Compounds like this often exhibit fluorescence, making them useful in bioimaging and as fluorescent probes in biological research.
  • Structure-Activity Relationship (SAR): The intricate structure of (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate allows for extensive studies into how modifications of its functional groups affect its biological activity. This can lead to the design of more effective derivatives with enhanced potency and selectivity.
  • Environmental Implications: As a quinoline derivative, understanding the degradation pathways of this compound in environmental contexts is crucial. Assessing its potential for persistence and bioaccumulation helps chemists mitigate any harmful ecological impacts.
  • Historical Significance: Quinoline and its derivatives have a rich history in organic chemistry, being associated with various natural products and synthetic pathways. Investigating compounds like (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate contributes to a broader understanding of chemical synthesis and reactivity.

In summary, the exploration of (7-nitro-8-quinolyl) 2,4-dimethoxybenzoate is not merely academic. As a bridge between theoretical chemistry and practical applications, it holds promise for advancements in both medicinal research and environmental safety, as exemplified by the quote:

"In science, there are no shortcuts to discovery." - A reminder to look deeper into the potential of compounds like this one.

Synonyms
BRN 1553654
BENZOIC ACID, 2,4-DIMETHOXY-, 7-NITRO-8-QUINOLYL ESTER
29002-51-5
8-Quinolinol, 7-nitro-, 2,4-dimethoxybenzoate
2,4-Dimethoxybenzoic acid 7-nitro-8-quinolyl ester
DTXSID30183214
RefChem:326561
DTXCID40105705
SCHEMBL4457999