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(7-nitro-8-quinolyl) 2,5-dimethoxybenzoate

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Identification
Molecular formula
C18H14N2O6
IUPAC name
(7-nitro-8-quinolyl) 2,5-dimethoxybenzoate
State
State

This compound is a solid at room temperature, given its melting point is significantly above room temperature, which is approximately 25°C.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.20
Boiling point (Celsius)
472.50
Boiling point (Kelvin)
745.70
General information
Molecular weight
372.35g/mol
Molar mass
372.3450g/mol
Density
1.4658g/cm3
Appearence

The substance is generally a solid due to its organic nature. It would be expected to appear crystalline or powdery, ranging from whitish to light yellow based on the nitro and methoxy functional groups present.

Comment on solubility

Solubility of (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate

The solubility of the compound (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate can be quite intriguing due to its structural characteristics. Understanding its solubility behavior is essential for applications in various fields including pharmaceuticals and material science.

Factors Influencing Solubility:

  • Polarity: This compound features both polar and nonpolar regions. The polarity influences how it interacts with solvents, particularly water and organic solvents.
  • Hydrogen Bonding: Presence of hydroxyl groups in similar compounds often enhances solubility in polar solvents due to hydrogen bonding capabilities.
  • Crystal Structure: The arrangement of molecules in the crystalline state can affect the solubility. Compounds with distorted packing often exhibit higher solubility.

In general, one might expect that (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate shows limited solubility in water but may dissolve in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol. This is largely due to its hydrophobic aromatic groups, which resist interaction with water molecules.

As a rule of thumb, when evaluating the solubility of organic compounds, remember the famous phrase: "Like dissolves like." Therefore, nonpolar compounds tend to dissolve well in nonpolar solvents, while polar compounds find better solubility in polar environments.

In conclusion, while (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate may not be readily soluble in aqueous conditions, its solubility in organic solvents provides useful options for its applications in laboratory and industrial settings.

Interesting facts

Exploring (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate

(7-nitro-8-quinolyl) 2,5-dimethoxybenzoate is a fascinating compound that combines elements of organic chemistry and medicinal applications. Here are some interesting insights:

  • Structure and Function: This compound features a quinoline moiety, which is a bicyclic structure known for its vibrant color and the ability to bind to metal ions, making it significant in coordination chemistry. The nitro group enhances its distinct features, contributing to its biological activity.
  • Applications in Science: It is often employed in the development of fluorescent probes. These probes help in visualizing cellular processes and tracking molecular interactions due to their unique photophysical properties.
  • Pharmacological Potential: Compounds like this one are invaluable in medicinal chemistry. They are investigated for their role in drug design, particularly against various pathogens and cancers, due to their bioactive components.
  • Multifaceted Synthesis: The synthesis of such compounds can be intricate, involving numerous steps of functionalization and purification. This complexity often leads to a rich exploration of new synthetic methodologies in the lab.
  • Research Opportunities: The structural diversity of (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate opens up numerous avenues for research, particularly in enhancing its potency and selectivity as a pharmaceutical agent or probe.

As we delve deeper into the realms of organic chemistry, compounds like (7-nitro-8-quinolyl) 2,5-dimethoxybenzoate remind us of the intricate dance between structure and function and the endless possibilities that lie in molecular innovation.

Synonyms
29007-63-4
BENZOIC ACID, 2,5-DIMETHOXY-, 7-NITRO-8-QUINOLYL ESTER
2,5-Dimethoxybenzoic acid 7-nitro-8-quinolyl ester
8-Quinolinol, 7-nitro-, 2,5-dimethoxybenzoate
DTXSID70183258
RefChem:326566
DTXCID80105749
SCHEMBL4471468