(7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate

Identification

Molecular formula

C₂₀H₁₆N₂O₆

CAS number

5453-67-2

IUPAC name

(7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate

State

The compound is typically a solid at room temperature, which is consistent with many organic compounds containing aromatic structures. These structures often contribute to a greater molecular packing efficiency, influencing the state as solid. The presence of nitro and methoxy groups can also enhance intermolecular interactions, stabilizing the solid state.

Melting point (Celsius)

221.00

Melting point (Kelvin)

494.15

Boiling point (Celsius)

505.00

Boiling point (Kelvin)

778.15

General information

Molecular weight

376.35g/mol

Molar mass

376.3540g/mol

Density

1.3379g/cm³

Appearence

The compound can appear as a crystalline solid, usually with a yellowish or brownish tint, reflecting its chemical structure that includes nitro and methoxy groups. These features can influence the coloration, making the appearance distinct among similar crystalline organic compounds.

Comment on solubility

Solubility of (7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate

The solubility characteristics of (7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate are important for understanding its behavior in various environments. This compound exhibits certain properties that influence its solubility in solvents:

Polar solvents: The presence of nitro and quinoline groups can lead to potential solubility in polar solvents due to the ability to form hydrogen bonds.
Apolar solvents: Conversely, the hydrophobic sections of the molecule suggest that the compound may also exhibit solubility in apolar solvents, albeit to a lesser extent.
pH dependence: The solubility may also vary with pH levels, highlighting the importance of environmental conditions on its dissolution behavior.
Temperature effects: It is likely that temperature plays a role, where increased temperatures can enhance the solubility of organic compounds.

In summary, while the exact solubility of (7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate may vary, it is generally understood to have a diverse solubility profile, influenced by factors including solvent type and external conditions. Understanding these factors is crucial for its application in chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts About (7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate

(7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate is a fascinating compound that piques the interest of chemists due to its unique structural characteristics and potential applications in various fields.

Key Features:

Complex Structure: This compound consists of a quinoline moiety, which is known for its role in many biological activities, making it a versatile scaffold in drug development.
Biological Significance: Research indicates that quinoline derivatives often exhibit antimicrobial, antimalarial, and anticancer properties, paving the way for innovative therapeutic agents.
Functional Groups: The presence of both nitro and methoxy functional groups enhances the reactivity and solubility of the compound, broadening its chemical versatility.

The **7-nitro** substitution is particularly interesting as it can influence the electronic properties and thus the biological activity of the molecule. This could lead to enhanced efficacy in drug formulations. Additionally, compounds featuring electronegative groups, like nitro, can interact with biological targets in a specific manner, potentially yielding promising pharmacological profiles.

Moreover, the inclusion of the **2,3-dimethoxyphenyl** group introduces structural diversity that can be leveraged in medicinal chemistry to optimize interactions with biological macromolecules.

Research and Applications:

Drug Design: This compound may serve as a lead compound for the synthesis of new medications targeting various diseases.
Material Science: The unique properties of quinolines make them interesting candidates for developing new materials with specific optical or electronic properties.
Biological Assays: Compounds like this are often used in laboratory settings to evaluate the activity of new drug candidates and their mechanisms of action.

In summary, (7-nitro-8-quinolyl) 3-(2,3-dimethoxyphenyl)prop-2-enoate is much more than just a chemical compound; it represents the intersection of synthetic chemistry and biological innovation, offering a plethora of research avenues yet to be explored.

Synonyms

SCHEMBL4459234