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7-Phenyl-1,2,3,4-tetrahydroisoquinolinium chloride

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Identification
Molecular formula
C15H16ClN
CAS number
6528-54-9
IUPAC name
7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

At room temperature, 7-Phenyl-1,2,3,4-tetrahydroisoquinolinium chloride primarily exists in a solid state.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
257.75g/mol
Molar mass
257.7520g/mol
Density
1.2200g/cm3
Appearence

The compound appears as a solid, typically in the form of a crystalline powder or fine granules. The color may vary from white to slightly off-white depending on the purity of the sample. It is generally odorless and stable under normal conditions.

Comment on solubility

Solubility of 7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride

The solubility of 7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride can be quite intriguing due to its ionic nature. Being a chloride salt, its solubility is predominantly influenced by the following factors:

  • Ionic Interactions: The compound consists of a positively charged ion (the tetrahydroisoquinolinium part) and a negatively charged chloride ion. Generally, ionic compounds tend to be soluble in polar solvents like water.
  • Influence of Substituents: The phenyl group may affect the solubility due to steric hindrance or electronic effects, potentially increasing hydrophobic interactions.
  • Temperature Dependency: Like many salts, the solubility of this compound may increase with temperature, making it more soluble in hot solvents compared to cold ones.
  • Common Solvents: Typical solvents for such compounds are water, methanol, and ethanol, though solubility can vary widely across different solvents.

In general, one could state that "the ability of ionic compounds to dissolve in polar solvents is well recognized," and this compound is likely no exception. It's important to conduct experiments to establish exact solubility limits under various conditions, as these factors can significantly alter the expected outcomes.

Interesting facts

Interesting Facts about 7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride

7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride is a fascinating compound that belongs to the class of tetrahydroisoquinolines, which are notable for their diverse biological activities and structural complexity. Here are some intriguing points about this compound:

  • Biological Significance: Compounds in the tetrahydroisoquinoline family have shown a range of biological properties, including anticancer, anti-inflammatory, and neuroprotective effects. This specific compound may exhibit unique interactions with biological systems.
  • Citation in Research: It has been the subject of various scientific studies, with researchers investigating its potential therapeutic applications. The structure allows exploration into its pharmacological activities, particularly in the realm of neuroscience and medicinal chemistry.
  • Nomenclature: The name indicates a complex structure characterized by a phenyl group attached to a tetrahydroisoquinoline backbone. This specific configuration is crucial for the compound's interaction with biological receptors and enzymes.
  • Applications in Chemistry: Beyond its biological properties, tetrahydroisoquinolines are used as intermediates in the synthesis of various pharmaceuticals and agrochemicals, showcasing their importance in modern organic synthesis.
  • Research Techniques: Investigating this compound often involves advanced methodologies such as NMR spectroscopy and mass spectrometry, which aid in determining its structure and studying its interactions.

In conclusion, 7-phenyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride is not just a simple chemical compound; it opens doors to extensive research pathways and has the potential for significant contributions to both medicinal chemistry and pharmacology. Researchers continue to uncover its mysteries, making it a compound of interest in the scientific community.

Synonyms
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-7-PHENYL-, HYDROCHLORIDE