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7-Phenyl-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C15H15N
CAS number
22929-79-5
IUPAC name
7-phenyl-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, 7-Phenyl-1,2,3,4-tetrahydroisoquinoline is in a solid state.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.20
Boiling point (Celsius)
344.10
Boiling point (Kelvin)
617.20
General information
Molecular weight
207.29g/mol
Molar mass
207.2850g/mol
Density
1.0815g/cm3
Appearence

7-Phenyl-1,2,3,4-tetrahydroisoquinoline typically appears as a white to off-white crystalline solid. The compound may exhibit different levels of crystallinity depending on the purification process.

Comment on solubility

Solubility of 7-phenyl-1,2,3,4-tetrahydroisoquinoline

7-phenyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound that exhibits unique solubility characteristics. Its solubility can be influenced by various factors, including:

  • Polarity: This compound is relatively non-polar due to its aromatic structure, leading to limited solubility in polar solvents like water.
  • Solvent Choices: It shows better solubility in organic solvents such as ethanol, chloroform, or dichloromethane, which can effectively dissolve non-polar compounds.
  • Temperature Effects: Increasing the temperature often enhances solubility for organic compounds, so this may also apply to 7-phenyl-1,2,3,4-tetrahydroisoquinoline.

In summary, while 7-phenyl-1,2,3,4-tetrahydroisoquinoline is poorly soluble in water, it can be effectively dissolved in a range of non-polar organic solvents. Understanding these solubility characteristics is crucial for its applications in various chemical reactions and formulations.

Interesting facts

Interesting Facts About 7-Phenyl-1,2,3,4-tetrahydroisoquinoline

7-Phenyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound that bridges the realms of organic chemistry and pharmacology. Here are some intriguing insights into this compound:

  • Structural Significance: As a member of the tetrahydroisoquinoline family, this compound possesses a unique bicyclic structure. Its configuration plays a pivotal role in determining its chemical reactivity and biological interactions.
  • Pharmacological Potential: Tetrahydroisoquinolines are known for their diverse biological activities. The 7-phenyl substitution on the isoquinoline backbone has been studied for potential anticancer and antioxidant properties, making this compound a point of interest in drug development.
  • Natural Occurrence: Isoquinoline alkaloids are often derived from various plants and have been identified in several medicinal herbs. This compound's structural analogs have shown therapeutic applications in traditional medicine, highlighting its historical significance.
  • Synthesis Challenges: The synthesis of 7-phenyl-1,2,3,4-tetrahydroisoquinoline can be quite challenging due to the need for precise stereochemistry. As a result, chemists often utilize advanced techniques, including catalysis and transition metal complexes, to enhance yield and control reaction pathways.
  • Research Implications: Ongoing studies continue to explore the compound's interactions at the molecular level, which could lead to innovative therapeutic strategies. This underscores the importance of understanding structure-activity relationships in drug design.

In summary, 7-phenyl-1,2,3,4-tetrahydroisoquinoline is not just a compound with remarkable structural properties, but it also holds potential for future medical applications. As research unfolds, the contributions it could make towards pharmacology and organic synthesis remain exciting!

Synonyms
7-phenyl-1,2,3,4-tetrahydroisoquinoline
24464-41-3
DTXSID00274946
RefChem:311255
DTXCID10226395
Isoquinoline, 1,2,3,4-tetrahydro-7-phenyl-
SCHEMBL4663734
CHEMBL4994599
SCHEMBL30593253
UQIVTFOULAOFAA-UHFFFAOYSA-N
AKOS011659790
DA-07744
7-phenyl-1,2,3,4-tetrahydro-isoquinoline
DB-209011
CS-0269830
EN300-226898