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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
7,9,11,12,14-pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one
State
State
Erythromycin is typically a solid powder at room temperature. In pharmaceutical formulations, it can be found in different states such as suspensions and topical ointments, but in its base form, it is a solid.
Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
970.15
Boiling point (Kelvin)
1 243.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9390g/mol
Density
1.2400g/cm3
Appearence

Erythromycin appears as a white to off-white crystalline powder. It may have a slight odor and is often supplied in powder form for various pharmaceutical formulations. The powder is typically prepared for use in oral, topical, or intravenous delivery forms and may be slightly yellowish depending on the formulation and storage conditions.

Comment on solubility

Solubility of 7,9,11,12,14-pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one

The solubility characteristics of the compound 7,9,11,12,14-pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one can be quite intricate due to its complex structure.

In general, the solubility of organic compounds can be influenced by several factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups suggests that this compound is likely to exhibit hydrophilic characteristics, increasing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl groups can form hydrogen bonds, both with each other and with solvent molecules, enhancing solubility in appropriate conditions.
  • Alkyl Groups: The incorporation of a 3-methyloxirane moiety introduces some hydrophobic character, which can reduce solubility in strictly polar solvents.
  • Dimensional Structure: The compound's intricate tetracyclic structure may hinder access to solvent molecules, potentially impacting its solubility.

Overall, it can be concluded that:

  • The solubility may be favorable in alcohol or other polar organic solvents.
  • It may exhibit limited solubility in non-polar environments due to its structural composition.

Thus, it is crucial to experimentally determine the solubility in various solvents to fully understand the behavior of this fascinating compound.

Interesting facts

Interesting Facts about 7,9,11,12,14-Pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one

This compound, often referred to for its complex structure, is notable for its multifaceted chemical characteristics and potential applications in various fields. Here are some fascinating points about this unique molecule:

  • Structural Complexity: Featuring a tetracyclic structure, the compound possesses multiple rings that create a distinctive 3D architecture, making it a subject of interest in both synthetic and natural product chemistry.
  • Hydroxyl Groups: The presence of five hydroxyl groups plays a crucial role in influencing the compound's reactivity and biological interactions, offering potential for remarkable therapeutic effects.
  • Oxirane Functionality: The incorporation of a 3-methyloxirane-2-carbonyl group enhances the compound's versatility, potentially facilitating interesting reaction pathways including ring-opening and nucleophilic attacks.
  • Biological Implications: Research into compounds with similar frameworks has shown potential for applications in antioxidant and antimicrobial activities, providing avenues for further investigation.
  • Complex Synthesis: The intricate synthesis of this compound may involve multiple steps, making it an exciting challenge for chemists who enjoy developing innovative synthetic strategies.

In summary, 7,9,11,12,14-pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one is not just a chemical entity; it's a testament to the vast and intricate world of organic chemistry, showcasing how molecular complexity can lead to diverse opportunities for research and application.

Synonyms
Cervicarcin
Cervicarcin, hemihydrate
18700-78-2
NSC65380
7,9,11,12,14-pentahydroxy-13-methyl-12-(3-methyloxirane-2-carbonyl)-15-oxatetracyclo[8.4.1.01,10.03,8]pentadeca-3(8),4,6-trien-2-one
NSC-65380
CHEMBL460290
DTXSID30940167
CHEBI:222979
TAA70078
HY-N15050
NCI60_018703
pentahydroxy-methyl-(3-methyloxirane-2-carbonyl)[?]one
4a, 1,2,3,4-tetrahydro-1,3,4,5,10-pentahydroxy-2-methyl-3-[(3-methyloxiranyl)carbonyl]-
1,3,4,5,10-Pentahydroxy-2-methyl-3-(3-methyloxirane-2-carbonyl)-1,2,3,4-tetrahydro-4a,9a-epoxyanthracen-9(10H)-one
1,3,4,5,10-Pentahydroxy-2-methyl-3-[(3-methyloxiran-2-yl)carbonyl]-1,2,3,4-tetrahydro-4a,9a-epoxyanthracen-9(10H)-one
3929-14-4
Anthrone,9a-epoxy-3-(2,3-epoxybutyryl)-1,2,3,4,4a,9a-hexahydro-1,3,4,5,10-pentahydroxy-2-methyl-
Anthrone,9a-epoxy-3-(2,3-epoxybutyryl)-1,2,3,4,4a,9a-hexahydro-1,3,4,5,10-pentahydroxy-2-methyl-, hemihydrate
Anthrone,9a.alpha.-epoxy-3.beta.-(2,3-epoxybutyryl)-1,2,3,4,4a,9a.alpha.-hexahydro-1.alpha.,3,4.alpha.,10.alpha.-tetrahydroxy-5-methoxy-2.beta.-methyl-