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Adenine

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Identification
Molecular formula
C5H5N5
CAS number
73-24-5
IUPAC name
7H-purin-2-amine
State
State

At room temperature, adenine is in a solid state.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
642.90
Boiling point (Kelvin)
916.05
General information
Molecular weight
135.13g/mol
Molar mass
135.1270g/mol
Density
1.6000g/cm3
Appearence

Adenine appears as a white to off-white crystalline powder. It is known for its relatively simple structure and high level of purity when prepared for biochemical applications.

Comment on solubility

Solubility of 7H-purin-2-amine

7H-purin-2-amine, also known as adenine, exhibits interesting solubility characteristics that are crucial for its biological functions and applications.

Solubility in Water

This compound is moderately soluble in water, which allows it to easily participate in various biochemical processes. Its solubility can be attributed to:

  • Hydrogen bonding: The amine group facilitates interactions with water molecules.
  • Structural characteristics: The fused ring structure contributes to its overall polar nature.

Solubility in Organic Solvents

In addition to its solubility in aqueous solutions, 7H-purin-2-amine exhibits:

  • Low solubility in non-polar solvents, such as hexane.
  • Limited solubility in organic solvents like ethanol and methanol.

This variability in solubility is essential to consider for applications in pharmaceutical formulations and biological systems. As adenine functions as a key component in nucleic acids, its solubility profile plays a significant role in nucleotide interactions and cellular processes.

Overall, understanding the solubility of 7H-purin-2-amine is vital for leveraging its potential in biological and chemical research.

Interesting facts

Interesting Facts about 7H-purin-2-amine

7H-purin-2-amine, also known as adenine, is a vital compound in the field of biochemistry and molecular biology. Here are some intriguing aspects of this essential purine base:

  • Fundamental Role in Nucleic Acids: Adenine is one of the four primary bases found in DNA and RNA, alongside thymine (in DNA), cytosine, and guanine. Its sequence within these nucleic acids is crucial for encoding genetic information.
  • Energy Currency: This compound forms part of adenosine triphosphate (ATP), which is known as the "energy currency" of the cell. ATP is essential for various cellular processes, providing the energy required for reactions and transport mechanisms.
  • Signal Transduction: Adenine derivatives, such as cyclic adenosine monophosphate (cAMP), play vital roles in signal transduction pathways, facilitating communication within cells and regulating numerous physiological functions.
  • Nutritional Importance: As a purine base, adenine is involved in the metabolism of nucleotides and is synthesized within the body. However, adenine can also be obtained from dietary sources, enabling various biochemical processes throughout the organism.
  • Potential Therapeutic Uses: Research has suggested that adenine and its derivatives may have therapeutic properties, playing roles in cell signaling and genetic regulation. This has opened new avenues for drug development and treatment strategies.

In summary, 7H-purin-2-amine is more than just a component of nucleic acids—it is a central player in energy metabolism, cellular signaling, and genetic expression. Its presence is pivotal, embodying life's molecular foundation.

Synonyms
2-aminopurine
7H-purin-2-amine
452-06-2
9H-Purin-2-amine
1H-PURIN-2-AMINE
Purine, 2-amino-
191236-69-8
Isoadenine
Aminopurine
SQ 22451
2-amino purine
2'-amino-purine
2-AP
7H-Purin-2-amine (9CI)
CCRIS 759
EINECS 207-197-4
UNII-O14B3U97FW
NSC 24129
O14B3U97FW
7H-Purin-2-ylamine
9H-Purin-2-ylamine
SQ 22,451
CHEBI:479072
AMINOPURINE, 2-
MFCD00005566
NSC-24129
CHEMBL388594
(9H-PURIN-2-YL)AMINE
DTXSID40196416
NSC24129
SQ-22451
2 Aminopurine
SMR000857109
9H-Purin-2-amine #
BiomolKI_000044
BiomolKI2_000050
7H-Purin-2-amine(9ci)
2-Aminopurine, >=99%
SCHEMBL5631
BMK1-E8
61655-24-1
MLS001333095
MLS001333096
DTXCID50118907
HMS2230L13
HMS3373E01
BCP32824
BDBM50208875
AKOS006220998
AKOS015961157
CCG-100648
CS-W013358
FA07967
HY-W012642
SDCCGMLS-0065821.P001
1H-Purine-2-amine; 9H-Purin-2-amine
NCGC00163382-01
AC-13347
PD044966
TS-00023
DB-008162
DB-220103
DB-264099
NS00031498
W13621
Q209313
Z2786042704
2BP