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Testosterone

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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
(7R)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
State
State
Testosterone is typically in a solid state at room temperature. It appears as white or slightly creamy-white crystals or crystalline powder. Under normal conditions, it remains stable when stored in a cool, dry place.
Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
369.00
Boiling point (Kelvin)
642.15
General information
Molecular weight
288.42g/mol
Molar mass
288.4240g/mol
Density
1.1200g/cm3
Appearence
Testosterone is typically a crystalline white to off-white powder. It may appear slightly cream-colored due to impurities and its crystalline form can reflect light, giving it a somewhat shiny appearance under a microscope.
Comment on solubility

Solubility of (7R)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one

The solubility of (7R)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one can be quite complex, given its intricate molecular structure. Understanding its solubility behavior is crucial for applications in various fields, including pharmaceuticals and organic chemistry.

Key Insights on Solubility

  • Polarity: The presence of hydroxyl (-OH) groups typically increases solubility in polar solvents, specifically water. However, the overall non-polar nature of the compound may limit its solubility.
  • Solvent Interaction: This compound is likely to show better solubility in organic solvents like ethanol or dimethyl sulfoxide (DMSO) rather than in water due to its large hydrophobic (non-polar) regions.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, allowing for more effective dissolution in higher temperatures.

In summary, while (7R)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one may exhibit limited solubility in water, it is expected to have favorable interactions with organic solvents, especially under increased temperatures. As always, thorough experimentation is recommended to determine precise solubility parameters.

Interesting facts

Interesting Facts about (7R)-17-Hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one

This compound is a fascinating example of a steroid, showcasing the complexity and versatility of natural organic molecules. Here are some intriguing highlights about this unique chemical:

  • Biological Significance: Compounds related to this structure can have notable implications in biological systems, particularly in the fields of hormonal activity and pharmacology. Understanding the nuances of such structures may lead to breakthroughs in drug development.
  • Chemical Structure: The intricate arrangement of cyclopenta[a]phenanthrene reflects a sophisticated architecture commonly found in steroids. The presence of multiple methyl groups and a hydroxy functional group significantly alters the compound's chemical reactivity and biological interactions.
  • Stereochemistry: The notation “(7R)” emphasizes the importance of stereochemistry in this molecule. Stereoisomers can exhibit dramatically different properties, which is crucial for their biological function. It's often said, "the structure dictates function," and this compound is a perfect illustration of that principle.
  • Potential Applications: Due to its structural characteristics, this compound may serve as a precursor for synthesizing various pharmaceuticals, including anabolic steroids and other therapeutics. Researchers are always keen to explore how slight modifications to such compounds can yield new materials with desirable properties.
  • Research Directions: Ongoing studies into this type of compound focus on characterizing its biological activity, potential therapeutic uses, and mechanisms of action. Innovations in synthetic methodologies continue to enhance the accessibility of such complex molecules for research and practical applications.

In summary, the (7R)-17-hydroxy-7,13-dimethyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one compound not only raises questions regarding its chemical behavior but also stimulates ideas for future research horizons in medicinal chemistry and natural product synthesis. As chemists delve deeper into its properties and effects, we can expect to unveil more about the intricate relationship between molecular structure and biological activity.

Synonyms
HMEO
YSGQGNQWBLYHPE-BRIGUCEYSA-N
PD008937
Q27095701