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Clavulanic Acid Amide Derivative

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Identification
Molecular formula
C15H17ClN2O5
CAS number
87354-53-8
IUPAC name
[(7R,8S)-11-amino-5-(2-chloroacetyl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State

At room temperature, this compound remains in a solid state. It is predominantly present as a crystalline powder, which not only influences its handling but also its application in various chemical reactions.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
370.76g/mol
Molar mass
370.7900g/mol
Density
1.4500g/cm3
Appearence

The compound typically appears as a crystalline powder, often white or off-white in color. Its crystalline nature and powdery form make it easy to handle in solid state reactions and formulations.

Comment on solubility

Solubility of [(7R,8S)-11-amino-5-(2-chloroacetyl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility characteristics of the compound [(7R,8S)-11-amino-5-(2-chloroacetyl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate can be quite intricate due to its complex molecular structure. Here are some key points to consider:

  • Solvent Dependent: The solubility of this compound can vary significantly depending on the solvent used.
  • Polar vs. Non-Polar Solvents: It is likely to exhibit higher solubility in polar solvents like water compared to non-polar solvents.
  • Influence of Functional Groups: The presence of functional groups, such as the carbamate and amino groups, can enhance solubility by improving hydrogen bonding capabilities.
  • Temperature Effects: Increasing temperature may enhance solubility, a common phenomenon observed in many compounds.

It is essential to note that solubility data may not always be readily available for complex synthetic compounds like this one, and experimental determination may be necessary. In conclusion, solubility is a critical factor that influences the compound's applicability and should be thoroughly explored in various solvent systems.

Interesting facts

Interesting Facts about the Compound: [(7R,8S)-11-amino-5-(2-chloroacetyl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This fascinating compound belongs to a class of chemicals known for their structural complexity and biological significance. Here are some interesting highlights:

  • Structural Intricacy: The compound features a tetracyclic structure, which is a characteristic that makes it particularly interesting for synthetic organic chemistry. Diverse cyclic structures often exhibit unique reactivity and properties.
  • Biological Relevance: Compounds with similar structures are often found in biologically active molecules, such as alkaloids or antibiotics. This specific compound may demonstrate a range of pharmacological activity.
  • Chiral Centers: The notation (7R,8S) in its name indicates the presence of chiral centers, meaning this compound can exist in different forms (enantiomers). These forms can have different biological effects, emphasizing the importance of stereochemistry in medicinal chemistry.
  • Research Potential: Given its intricate structure and the presence of functional groups like the amino and carbamate moieties, this compound is a promising candidate for further research in the fields of drug development and biochemistry.
  • Mechanism of Action: Understanding how similar compounds interact at the molecular level can provide insights into developing new therapeutic agents that are more effective and have fewer side effects.

Overall, this compound showcases the intricate and often beautiful designs nature and synthetic chemistry can achieve, inviting continued exploration and discovery in the vast landscape of chemical science.

Synonyms
BRN 0903753
18341-86-1
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-1-(chloroacetyl)-8-(hydroxymethyl)-8a-methoxy-5-methyl-, carbamate (ester)
DTXSID70939717
[6-Amino-1-(chloroacetyl)-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl hydrogen carbonimidate