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Oxaliplatin

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Identification
Molecular formula
C8H14N2O2
CAS number
61825-94-3
IUPAC name
[(7R,8S)-11-amino-7-hydroxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State

Oxaliplatin is a solid at room temperature.

Melting point (Celsius)
198.50
Melting point (Kelvin)
471.60
Boiling point (Celsius)
206.10
Boiling point (Kelvin)
479.20
General information
Molecular weight
397.29g/mol
Molar mass
397.2860g/mol
Density
1.9320g/cm3
Appearence

Oxaliplatin is generally found as a white or off-white crystalline powder.

Comment on solubility

Solubility of [(7R,8S)-11-amino-7-hydroxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility characteristics of the compound C8H14N2O2 can be outlined with a focus on several key aspects:

  • Polarity: The presence of multiple functional groups, including an amino group and hydroxyl group, typically enhances solubility in polar solvents such as water.
  • Hydrogen bonding: The capability of forming hydrogen bonds is significant, as this encourages interaction with water molecules, potentially increasing solubility.
  • Hydrophobic interactions: The aromatic structure and hydrocarbon chain may exhibit hydrophobic properties, which could result in limited solubility in highly polar solvents.
  • Solvent choice: Given its structural characteristics, this compound may demonstrate variable solubility depending on the solvent employed. It may be more soluble in organic solvents such as ethanol or methanol as compared to water.

Overall, the solubility of this compound is expected to be moderate, being significantly influenced by both its polar and non-polar features. Further experimentation is essential to delineate precise solubility values across various environments.

Interesting facts

Interesting Facts about [(7R,8S)-11-amino-7-hydroxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This remarkable compound opens a gateway to numerous fascinating insights within the realm of organic chemistry and pharmacology. Often referenced in the context of its complex structure, this molecule embodies the intricate relationship between chemical structure and biological activity. Here are some intriguing points to note:

  • Structural Complexity: The compound features a tetracyclic backbone, which is quite rare and highlights the elaborate nature of its design. Its multi-ring structure is indicative of many natural products that exhibit diverse bioactivity.
  • Potential Therapeutic Applications: Compounds of this class often emerge from research focusing on novel therapeutic agents. The presence of amino and hydroxy groups suggests potential interactions with biological targets akin to peptide-based drugs.
  • Role of Stereochemistry: The (7R,8S) configuration indicates specific spatial arrangements that could significantly influence the compound's effectiveness and interactions within biological systems. Such stereochemical considerations are crucial when developing drugs, as they can dictate pharmacokinetics and pharmacodynamics.
  • Environmental Relevance: Carbamates, like the methyl carbamate backbone of this compound, are of interest due to their roles in agriculture as pesticides and herbicides, as well as their environmental impact and degradation pathways.
  • Research Interest: Due to its complex structure and potential applications, this compound is of ongoing interest in synthetic organic chemistry, where chemists strive to devise efficient synthesis methods and evaluate biological properties.

In conclusion, the study of [(7R,8S)-11-amino-7-hydroxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate illustrates the intricate dance between structure and function in organic molecules, paving the way for new discoveries in the field of chemistry.

Synonyms
DTXSID40906491
Q22259967
(6-Amino-8a-hydroxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl hydrogen carbonimidate
[(7R,8S)-11-Amino-7-hydroxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate