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Erlotinib

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Identification
Molecular formula
C22H23N3O4
CAS number
183321-74-6
IUPAC name
[(7R,8S)-11-anilino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State
At room temperature, erlotinib hydrochloride is in a stable solid state. It is usually processed into tablet form for medical applications.
Melting point (Celsius)
223.50
Melting point (Kelvin)
496.65
Boiling point (Celsius)
730.15
Boiling point (Kelvin)
1 003.15
General information
Molecular weight
393.44g/mol
Molar mass
393.4350g/mol
Density
1.3750g/cm3
Appearence
Erlotinib hydrochloride is typically observed as a white to slightly yellow solid powder. It is not visibly distinctive, but its structural properties and reactivity in chemical environments make it of particular interest in pharmaceutical applications.
Comment on solubility

Solubility of [(7R,8S)-11-anilino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility of the compound [(7R,8S)-11-anilino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate can be quite complex due to its intricate structure. The solubility characteristics are influenced by various factors, which can be summarized as follows:

  • Polarity: The presence of polar functional groups such as carbamate can enhance solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds may increase solubility in aqueous solutions.
  • Molecular Size: The large molecular framework may hinder solubility due to steric factors.
  • Temperature: Increased temperature often leads to enhanced solubility for many organic compounds.

Generally, it is observed that compounds with significant structural complexity, like this one, tend to exhibit variable solubility profiles depending on the solvent being used. It is essential to perform empirical testing to determine the exact solubility in different media. For practical applications, the solubility in organic solvents such as DMSO or ethanol may be more favorable than in water, due to the amphiphilic nature of the compound.

In conclusion, while the intricate nature of the compound suggests some hurdles in solubility, understanding its chemical properties can aid in optimizing conditions for effective use in relevant applications.

Interesting facts

Exploring the Unique Features of [(7R,8S)-11-anilino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This fascinating compound, often recognized for its complex structure and potential applications, belongs to a class of innovative chemical compounds that can play significant roles in various fields. Here are some intriguing aspects:

  • Structural Complexity: The compound features a distinctive tetracyclic framework, which presents unique challenges and opportunities in synthetic chemistry.
  • Medical Relevance: This compound may exhibit pharmacological properties, potentially serving as a lead compound in drug discovery. Its unique anilino group could interact with biological targets in innovative ways.
  • Mechanism of Action: Compounds with similar structures often function through modulation of enzyme activity or acting as receptor ligands. The intricacies of its mechanism can provide valuable insights during research.
  • Potential Applications: With ongoing research, derivatives of this compound could play roles in treating various conditions, possibly relating to cancer or other diseases due to their complex interaction mechanisms.
  • Synthesis: The synthesis of such complex structures is a feat of organic chemistry, often requiring multi-step reactions that highlight the ingenuity of chemists.

As scientists delve deeper into its properties, they may uncover further applications and insights that could revolutionize our understanding of chemical behavior and therapeutic possibilities. The intricacies of this compound encapsulate the mesmerizing world of chemical research, where each discovery opens the door to new horizons.