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Mitomycin C

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Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
[(7R,8S)-11-(aziridin-1-yl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State

Mitomycin C is found in a solid state at room temperature. As a stable crystalline powder, it is typically stored in a freezer and should be protected from light to preserve its stability and efficacy.

Melting point (Celsius)
360.15
Melting point (Kelvin)
633.30
Boiling point (Celsius)
274.85
Boiling point (Kelvin)
548.00
General information
Molecular weight
334.33g/mol
Molar mass
334.3260g/mol
Density
1.3000g/cm3
Appearence

Mitomycin C is a purple crystalline solid. It typically appears as a blue-violet crystalline powder when in its pure form and can also form solutions that exhibit a similar blue-violet hue. This compound has been used extensively in clinical settings, especially noted for its vivid coloration.

Comment on solubility

Solubility of [(7R,8S)-11-(aziridin-1-yl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility of the complex compound [(7R,8S)-11-(aziridin-1-yl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate poses intriguing challenges and characteristics. Here are some key points to consider:

  • Polarity: The presence of multiple functional groups, including carbamate and methoxy, suggests a balance of polar and nonpolar characteristics. This may impact its solubility in different solvents.
  • Solvent Compatibility: It is likely to be soluble in polar solvents such as methanol and dimethyl sulfoxide (DMSO), but may present limited solubility in nonpolar solvents like hexane or toluene.
  • Hydrogen Bonding: The ability to engage in hydrogen bonding can enhance solubility in polar solvents, while steric hindrance from the bulky framework might inhibit it in less polar mediums.
  • Temperature Effects: Solubility is often temperature-dependent; thus, heating the solvent may increase the dissociation of the compound into solution.

Considering its intricate structure and potential for various interactions, the solubility of this compound needs to be assessed experimentally to draw definitive conclusions. As stated, "the complex nature of chemical structures frequently lends to the subtle interplay of solubility factors."

Interesting facts

Interesting Facts about [(7R,8S)-11-(aziridin-1-yl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This compound is a fascinating example of the intricate designs found in organic chemistry, particularly in the realm of medicinal compounds. Its structure presents a unique configuration resulting in potential biochemical applications. Here are some remarkable aspects to consider:

  • Complex Structure: The compound features a multi-ring system, indicating its potential for unique interactions within biological systems.
  • Aziridine Ring: The presence of an aziridine moiety is noteworthy. Aziridines are known for their reactivity and ability to serve as building blocks in various organic reactions, making them valuable in the synthesis of pharmaceuticals.
  • Biological Activity: Compounds with similar structures have been researched for their antitumor properties. The unique arrangement of substituents might influence its efficacy and mechanism of action.
  • Carbamate Functionality: The incorporation of the carbamate group enhances the compound's stability and may also contribute to its bioactivity by impacting how it interacts with biological targets.

As one delves deeper into the chemistry of this compound, the implications for drug design and development are intriguing. "Understanding the structure-activity relationship can lead to the design of more effective therapeutic agents," is a quote often highlighted in medicinal chemistry discussions. This compound serves as an excellent example of how intricate molecular designs can lead to significant advances in health science and technology.


Synonyms
DTXSID80927302
[6-(Aziridin-1-yl)-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl hydrogen carbonimidate
13164-87-9