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Mitomycin C

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Identification
Molecular formula
C15H18N4O5
CAS number
50-07-7
IUPAC name
[(7R,8S)-11-(aziridin-1-yl)-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State

At room temperature, Mitomycin C is in solid state, existing as a crystalline powder. It should be stored in a dry, dark place to maintain its stability.

Melting point (Celsius)
360.00
Melting point (Kelvin)
633.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
334.32g/mol
Molar mass
334.3150g/mol
Density
1.3000g/cm3
Appearence

Mitomycin C appears as a blue-violet crystalline powder. When pure, it is practically odorless and is sensitive to light exposure. The compound is stable under ordinary conditions, but it should be handled with care due to its cytotoxic properties.

Comment on solubility

Solubility Overview

The compound (7R,8S)-11-(aziridin-1-yl)-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate exhibits specific solubility characteristics that can be crucial for its applications in various fields. Understanding its behavior in different solvents can provide insights into its reactivity, stability, and potential uses.

Factors Influencing Solubility

Several factors affect the solubility of this compound:

  • Polarity: The presence of polar functional groups, such as the carbamate and methoxy groups, can enhance solubility in polar solvents like water and alcohols.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules may contribute to greater solvation and thus increased solubility.
  • Molecular Weight: Higher molecular weight generally leads to lower solubility, which might be a consideration for this relatively complex compound.

Common Solvents

In practical applications, the solubility of this compound is best assessed in:

  • Water: May demonstrate limited solubility depending on pH and temperature.
  • Organic solvents: Such as ethanol or dimethyl sulfoxide (DMSO), which may provide better solubility due to their ability to interact with nonpolar and polar regions of the molecule.
  • Aqueous buffers: Can be used for enhanced solubility in a more controlled environment, optimizing conditions for stability and reactivity.

In conclusion, the solubility of (7R,8S)-11-(aziridin-1-yl)-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate is influenced by several factors, particularly its polarity and ability to form hydrogen bonds. Evaluating solubility in various solvents not only informs practical applications but also helps in understanding its chemical behavior.

Interesting facts

Interesting Facts About [(7R,8S)-11-(aziridin-1-yl)-7-methoxy-5,12-dimethyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This unique compound is a fascinating example of complex organic chemistry due to its intricate structure and potential applications. Below are some of the intriguing aspects of this compound:

  • Stereochemistry: The compound features two chiral centers at the 7R and 8S positions, greatly influencing its biological activity. Stereochemistry plays a crucial role in drug design and efficacy.
  • Aziridine Ring: The presence of the aziridine ring contributes to its reactivity and can influence the compound's interaction with biological targets. Aziridines are known for their strain and are valuable molecules in synthetic chemistry.
  • Biological Relevance: Compounds with similar structures often exhibit antiviral, anticancer, and antimicrobial properties. Understanding the behavior of this compound could lead to new therapeutic agents.
  • Carbamate Moiety: The methyl carbamate group enhances the compound's stability and solubility, making it a noteworthy candidate for further pharmacological studies.
  • Potential Applications: With its multifaceted structure, this compound might be explored in various applications ranging from drug discovery to materials science.

As a chemistry student or scientist, delving into the unique attributes of such a compound can unveil not only the complexity of organic synthesis but also the potential it holds for innovative applications. In the words of a prominent chemist, "The beauty of chemistry lies in the understanding of its intricate mechanisms and the endless possibilities they present."