Ertapenem | Solubility of Things

Identification

Molecular formula

C₂₂H₂₅N₃O₇

CAS number

153832-46-3

IUPAC name

[(7R,8S)-11-(cyclohexylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

State

Ertapenem is generally a solid at room temperature, and it is supplied primarily as a lyophilized powder intended for solution reconstitution.

Melting point (Celsius)

204.00

Melting point (Kelvin)

477.15

Boiling point (Celsius)

300.00

Boiling point (Kelvin)

573.15

General information

Molecular weight

497.50g/mol

Molar mass

497.5000g/mol

Density

1.5500g/cm³

Appearence

Ertapenem, in its pure form, appears as a white to off-white crystalline powder. The compound is generally provided in a lyophilized form for clinical use.

Comment on solubility

Solubility of [(7R,8S)-11-(cyclohexylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility of this compound, a complex organic molecule, can be influenced by several key factors. Here are some important considerations:

Polarity: The presence of functional groups such as the carbamate moiety may enhance solubility in polar solvents, while the overall structure's hydrophobic regions can limit solubility in water.
Solvent Selection: Solubility often varies with different solvents. It is generally more soluble in organic solvents such as acetone or ethanol compared to water.
Temperature: As is typical with many compounds, solubility may increase with rising temperatures, making it more readily dissolvable, particularly in organic solvents.
Effect of pH: For compounds containing functional groups that can ionize, altering the pH of the solution can significantly affect solubility by affecting the ionization state of the molecule.

In summary, predicting the solubility of [(7R,8S)-11-(cyclohexylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate requires careful consideration of its molecular characteristics and the conditions under which it is dissolved. Generally speaking, with its intricate structure, it is likely to show higher solubility in organic solvents than in polar aqueous environments.

Interesting facts

Interesting Facts about [(7R,8S)-11-(cyclohexylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This complex compound, characterized by its intricate structure, falls into the category of pharmaceutical intermediates. Known for its potential therapeutic uses, it showcases how multidisciplinary approaches in chemistry can lead to discoveries that impact human health. Here are some interesting facts:

Structural Significance: The presence of multiple rings and functional groups in the structure creates a unique framework that can influence its biological activity.
Cyclohexylamino Group: The cyclohexylamino moiety contributes to the compound's ability to interact with biological receptors, making it a subject of interest in medicinal chemistry.
Research Potential: Compounds with similar frameworks are often investigated for their roles in enzyme inhibition or as potential drug candidates for various conditions.
Synthesis Challenges: The synthesis of such complex molecules can pose significant challenges, requiring advanced techniques in organic chemistry, such as multistep synthesis and regioselective modifications.
Future Applications: With ongoing studies and the promising nature of its structure, researchers are keen on exploring its application in fields like cancer therapy and antibiotic development.

The investigation into the properties and effects of this compound presents a fascinating example of how molecular design and synthesis can lead to groundbreaking advancements in pharmacology. As the field of chemistry evolves, compounds like this hold the key to unlocking new treatments and understanding complex biological systems.