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Etoposide

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Identification
Molecular formula
C29H32O13N4
CAS number
33419-42-0
IUPAC name
[(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State
Solid
Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
588.57g/mol
Molar mass
588.5730g/mol
Density
1.8000g/cm3
Appearence

Etoposide is found as a white to yellowish crystalline powder. The compound is poorly soluble in water but soluble in organic solvents such as ethanol and dimethyl sulfoxide.

Comment on solubility

Solubility Characteristics of [(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

The solubility of the compound [(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate can significantly affect its practical applications in various fields. Understanding its solubility profile is essential and can be outlined as follows:

  • Polarity: The presence of various functional groups, such as carbamate and ethylamino, typically influences solubility. Polar compounds tend to be more soluble in polar solvents (e.g., water).
  • Solvent Compatibility: This compound may show different solubility levels in common solvents like:
    • Water: Depending on ionic or hydrogen-bonding characteristics.
    • Alcohols: Generally higher solubility due to polar interactions.
    • Organic solvents: Solubility can vary, particularly in less polar environments.
  • Temperature Dependence: As with many compounds, solubility could increase with temperature, suggesting that heating solvents before dissolution may be beneficial.
  • pH Influence: The solubility of this compound might also be pH-dependent, particularly due to protonation states of the amino groups.

In summary, the solubility of [(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate may vary significantly based on factors such as polarity, solvent type, temperature, and pH. Understanding these characteristics helps in optimizing the compound's use in practical applications and facilitates the development of formulations or reactions.

Interesting facts

Interesting Facts about [(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

This compound is a fascinating example of a complex organic molecule that showcases the diversity and the intricacy of chemical structures. It belongs to a class of compounds known as carbamates, which are notable for their wide range of applications in agriculture and pharmaceuticals.

Molecular Complexity

The stereochemistry of this compound, indicated by its specific configuration, suggests a detailed mechanism of action that can be explored. Here are some highlights regarding its structure:

  • Chirality: The presence of chiral centers means that this compound can exist in multiple stereoisomeric forms, which can lead to different biological activities.
  • Multiple Functional Groups: The combination of methoxy, ethylamino, and carbamate groups contributes to its reactivity and potential interactions with biological systems.
  • Complex Framework: This compound features a tetracyclic core, making it a member of a unique class of molecules that could be further studied for their physicochemical properties.

Applications

Due to its chemical structure, this compound is likely of interest in various fields:

  • Pharmacology: Such complex molecules are often found in drug development, where their specific configurations can enhance therapeutic effects.
  • Agricultural Chemistry: The interplay of functional groups in carbamates makes them promising candidates for pesticides or herbicides.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This compound certainly exemplifies that idea, inspiring further investigation into its potential uses and mechanisms.

In summary, the complexity and potential applications of [(7R,8S)-11-(ethylamino)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate mark it as an intriguing subject for both study and application in chemical sciences.