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Tetracycline

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Identification
Molecular formula
C22H24N2O8
CAS number
60-54-8
IUPAC name
[(7R,8S)-7-methoxy-12-methyl-10,13-dioxo-11-pyrrolidin-1-yl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
State
State

At room temperature, tetracycline is in a solid state. Its crystalline form makes it suitable for formation into tablet forms when used in medical applications. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
396.15
Boiling point (Kelvin)
669.30
General information
Molecular weight
444.44g/mol
Molar mass
444.4350g/mol
Density
1.5008g/cm3
Appearence

Tetracycline appears as yellow crystalline powder. It is a hygroscopic compound, which means it can absorb moisture from the air, affecting its handling and storage. The coloration and physical form are distinctive and aid in its identification.

Comment on solubility

Solubility of [(7R,8S)-7-methoxy-12-methyl-10,13-dioxo-11-pyrrolidin-1-yl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate

Understanding the solubility of this complex compound is pivotal for its applications in both medicinal chemistry and material science. The solubility of chemical compounds depends on a variety of factors including polarity, molecular structure, and intermolecular interactions. Here are some key points to consider:

  • Polarity: Compounds that have both polar and non-polar functional groups tend to exhibit amphiphilic properties, which can enhance solubility in a range of solvents.
  • Solvent Interaction: Solubility often varies significantly depending on the solvent used. For instance, organic solvents like ethanol or acetone might dissolve this compound more efficiently than water due to similar polarities.
  • Molecular Structure: The intricate structure of this compound suggests that it may have multiple sites for hydrogen bonding, which could enhance solubility in specific solvent environments.
  • Temperature and Pressure: Increasing temperature generally increases the solubility of solids in liquids, and this could be a relevant factor for dissolution behavior.

The solubility behavior of this compound remains to be thoroughly investigated. As with many compounds featuring multiple functional groups and complex structures, it’s crucial to conduct solubility tests across different solvents to map its solubility profile accurately. Overall, while the theoretical aspects give us a glimpse into potential solubility, empirical data will provide the definitive answers.

Interesting facts

Exploring the Unique Characteristics of a Complex Compound

The compound (7R,8S)-7-methoxy-12-methyl-10,13-dioxo-11-pyrrolidin-1-yl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl methyl carbamate is an intriguing example of the complexity found within organic chemistry. It features several notable characteristics that make it stand out:

  • Cyclic Structure: This compound contains a tetracyclic structure which adds layers of stability and complexity, a theme often explored in organic synthesis.
  • Diverse Functional Groups: The presence of a methoxy group, dioxo groups, and a carbamate moiety generates interesting chemical reactivity and potential applications.
  • Stereochemistry: With specific chiral centers indicated by the (7R,8S) configuration, this compound exemplifies the importance of stereochemistry in influencing biological activity and properties.
  • Potential Applications: Compounds with such intricate structures can serve as leads in drug discovery, particularly in developing new pharmaceuticals that target specific enzymes or receptors.

As a chemistry student or scientist, one might ponder the synthetic pathways that could lead to the formation of such a compound. Traditional organic synthesis methods could be applied, but it may also warrant the exploration of innovative techniques, such as:

  1. Modern coupling reactions to create complex carbon backbones.
  2. Selective reduction techniques to form the required functional groups.
  3. Stereoselective synthesis protocols to ensure the right isomer is produced.

In conclusion, the multifaceted nature of this compound not only makes it an exciting topic of study but also showcases the evolution of chemical synthesis and its implications in science. As you dive deeper into the realm of organic chemistry, remember that compounds like this serve as the junctions where creativity meets logic!