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Arecoline chloride

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Identification
Molecular formula
C13H22ClNO3
CAS number
300-08-3
IUPAC name
[(7S)-7-hydroxy-3,4,5,6,7,8-hexahydropyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-butanoate;chloride
State
State
At room temperature, Arecoline chloride is generally a solid and exists as white crystalline powder.
Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
331.15
Boiling point (Kelvin)
604.30
General information
Molecular weight
215.70g/mol
Molar mass
215.7000g/mol
Density
1.2000g/cm3
Appearence

Arecoline chloride is typically found as a white or off-white crystalline powder. It is highly soluble in water and may appear as a solution when dissolved.

Comment on solubility

Solubility of [(7S)-7-hydroxy-3,4,5,6,7,8-hexahydropyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-butanoate;chloride

The solubility of a compound can significantly affect its application and behavior in various environments. For the compound [(7S)-7-hydroxy-3,4,5,6,7,8-hexahydropyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-butanoate;chloride, we can highlight several important points regarding its solubility:

  • Polarity: The presence of multiple functional groups such as hydroxyl (-OH) and ammonium (-NH3+) suggests that the compound is likely to be polar. Polar compounds tend to have higher solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl groups can form extensive hydrogen bonds with water molecules, which can enhance the solubility of this compound in aqueous solutions.
  • Salt Formation: The chloride ion in the compound may facilitate its solubility in water due to its ionic nature, further indicating its potential as a soluble salt.
  • Structure-Activity Relationship: The specific arrangement of atoms in the hexahydropyrrolizin structure could impact how it interacts with solvents, potentially affecting solubility in organic solvents as well.

In conclusion, the solubility of this compound can be anticipated to be generally favorable in polar solvents, especially water, due to its polar functional groups and the presence of the chloride. However, detailed experimental solubility tests are essential to confirm these predictions.

Interesting facts

Interesting Facts about [(7S)-7-hydroxy-3,4,5,6,7,8-hexahydropyrrolizin-4-ium-1-yl]methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methyl-butanoate; chloride

This fascinating compound, often referred to as a curious member of the alkaloid family, contains a unique blend of structural features that contribute to its chemical behavior. Here are some intriguing aspects:

  • Complex Structure: The compound includes a hexahydropyrrolizin moiety, which is known for its role in various biological activities, especially in natural products and pharmaceuticals.
  • Bioactivity: Compounds similar to this one have been studied for their potential therapeutic effects. They may exhibit a variety of biological activities, including antimicrobial and anti-inflammatory properties.
  • Chirality: The presence of a chiral center in the compound indicates that it exists in different enantiomeric forms, which can have vastly different biological activity and metabolism in organisms.
  • Synthetic Pathways: This compound can be synthesized through several innovative chemical reactions that involve multiple steps, showcasing the creativity required in synthetic chemistry.

As a result of its unique features and potential applications, this compound serves as a prime example for chemists interested in the field of medicinal chemistry and natural product synthesis. It opens up avenues for research into its efficacy and mechanisms, making it a compound of significant interest among scientists.

Synonyms
26131-12-4
DTXSID30949019
(1-Hydroxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl 2-hydroxy-2-(1-hydroxyethyl)-3-methylbutanoate--hydrogen chloride (1/1)
RefChem:1049258
DTXCID001377226
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