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Tunicamycin

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Identification
Molecular formula
C41H63N3O17
CAS number
11089-65-9
IUPAC name
[(7S,11S,12R,13S,14R,15R,16R,17S,18S)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
State
State

At room temperature, tunicamycin is generally in a solid state, appearing as a powder used mainly in biological and biochemical applications.

Melting point (Celsius)
242.00
Melting point (Kelvin)
515.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
859.02g/mol
Molar mass
859.0240g/mol
Density
1.3205g/cm3
Appearence

Tunicamycin appears as a white to off-white powder. It is typically amorphous and may appear in various formulations such as lyophilized powder.

Comment on solubility

Solubility Characteristics

The solubility of the compound [(7S,11S,12R,13S,14R,15R,16R,17S,18S)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate can be quite complex due to its intricate structure. Here are some key points to consider:

  • Polarity: The presence of multiple hydroxyl groups (hydroxides, -OH) suggests that this compound may have increased polarity, which typically enhances solubility in polar solvents such as water.
  • Hydrophilic versus Hydrophobic Regions: The balance between hydrophilic portions (like -OH groups) and hydrophobic regions (such as the long hydrocarbon chains) will critically influence solubility.
  • Solvent Compatibility: It is likely to exhibit good solubility in alcohols or ether-based solvents due to its mixed functional groups.
  • pH Sensitivity: The solubility could also vary significantly with pH levels, particularly because of the potential for ionization of the hydroxyl groups.

In conclusion, while the compound may demonstrate a certain level of solubility in polar solvents, its complex structure could also present challenges in solubility depending on specific conditions and solvent interactions.

Interesting facts

Interesting Facts about the Compound

The compound in question is a fascinating example of complex organic chemistry, showcasing a myriad of functional groups and structural intricacies. Here are some engaging highlights about this unique compound:

  • Structural Complexity: This compound exhibits an extensive multifaceted structure, which includes multiple hydroxy groups and methoxy groups, indicating the presence of various reactive sites. The complexity of the molecular architecture is reflective of advanced synthetic capabilities in modern organic chemistry.
  • Natural Occurrence: Compounds with similar structural frameworks are often found in nature. Many natural products, especially those derived from plants, possess intricate structures that can exhibit remarkable biological activity. This compound may be related to natural substances with potential medicinal properties.
  • Potential Applications: Due to its elaborate framework, the compound may be of interest in drug design and development. Compounds with multiple functional groups can engage in diverse interactions in biological systems, enhancing their potential as pharmaceuticals.
  • Chirality and Isomerism: The presence of several chiral centers in this molecule plays a critical role in determining its spatial orientation, which can significantly influence its pharmacological properties. Such compounds must be synthesized with precision to ensure the desired chirality is maintained.
  • Research Significance: The study of complex compounds like this one is essential to expand our understanding of molecular interactions. Researchers often explore the synthesis and reactions of similar compounds to uncover new chemistry, revealing insights into their stability and reactivity.

Each aspect of this compound, from its unique functional groups to its potential applications, highlights the sophisticated nature of organic chemistry and the ongoing quest for new discoveries in the field.

Synonyms
NS00121953