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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[(7S,11S,12R,13S,14R,15R,16R,17S,18S)-27-[2-(diethylamino)-2-oxo-ethoxy]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
State
State
Erythromycin is typically found as a solid at room temperature, often in the form of a crystalline powder.
Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
833.50
Boiling point (Kelvin)
1 106.65
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2400g/cm3
Appearence

Erythromycin is a white or slightly yellow crystalline powder. It is commonly odorless, although it can have a faint characteristic odor. It is slightly soluble in water and freely soluble in alcohol and other organic solvents.

Comment on solubility

Solubility of the Compound

The compound [(7S,11S,12R,13S,14R,15R,16R,17S,18S)-27-[2-(diethylamino)-2-oxo-ethoxy]-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate encompasses a complex structure that significantly influences its solubility in various solvents.

This compound demonstrates:

  • High solubility in organic solvents: Due to its long hydrophobic chains and functional groups, it tends to dissolve well in non-polar solvents like chloroform, ethanol, and dimethyl sulfoxide (DMSO).
  • Limited water solubility: The presence of hydrophobic regions generally restricts solubility in water, although some solubility can occur via hydrogen bonding with the hydroxyl (-OH) groups.

In practical applications, the solubility profile can be summarized:

  1. Polar solvents: Minimal solubility, primarily due to the bulky structure.
  2. Non-polar solvents: Enhanced solubility, allowing for efficient extraction and formulation processes.

As such, understanding the solubility characteristics is essential for the effective use of this compound in formulations, impacting both its stability and bioavailability. For appropriate usage, one must consider these solubility traits to optimize application conditions.

Interesting facts

Interesting Facts about the Compound

This fascinating compound is a complex organic molecule with notable significance in the field of medicinal chemistry. It belongs to a class of compounds known for their diverse biological activities and therapeutic potentials. Here are some key facts that highlight its importance:

  • Biological Activity: Compounds with such intricate structures are often studied for their role in pharmaceuticals, particularly in antibiotic, anti-inflammatory, and anticancer applications.
  • Stereochemistry: The designation of stereochemical configuration in this compound (7S, 11S, etc.) suggests it exhibits specific spatial arrangements, which can dramatically affect its biological interactions and efficacy.
  • Complexity and Diversity: The extensive list of functional groups within this molecule showcases the diversity found in natural products and their derivatives. These functional groups can be crucial for interacting with biological targets.
  • Utilization of Amino Moiety: The presence of a diethylamino group infers potential for enhanced solubility and bioavailability, making it an interesting subject for drug design.
  • Research Potential: Due to its unique structure and proposed activities, this compound may serve as a lead compound in the development of new therapeutic agents.

As a scholar or enthusiast in chemistry, one cannot help but be intrigued by how such structurally elaborate molecules can foster advancements in medicine. Understanding their synthetic pathways and biological implications fuels ongoing research that aims to harness their full potential. As Albert Einstein once said, "Pure mathematics is, in its way, the poetry of logical ideas." In similar spirit, the study of complex compounds allows us to explore the intricate 'poetry' of nature’s chemistry.