Interesting facts
Interesting Facts about (7S,9S)-7-(4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; hydrochloride
This complex organic compound has been of great interest in pharmaceutical chemistry due to its intricate structure and potential biological applications. Here are some fascinating aspects:
- Bioactivity: The compound exhibits promising biological activities, particularly in the fields of antimicrobial and anti-inflammatory research. Its specific substitutions play crucial roles in enhancing its biological properties.
- Synthesis Complexity: The synthesis of this compound involves multiple reaction steps, showcasing the artistry of organic synthesis. The introduction of the tetrahydropyran moiety is particularly noteworthy as it adds complexity to the overall structure.
- Structure-Activity Relationship: Studying the structure-activity relationship leads to a better understanding of how slight changes in the molecular structure can significantly affect biological activity. Researchers focus on how different functional groups influence the effectiveness of the compound.
- Potential Applications: Beyond its possible therapeutic uses, this compound could serve as a model for developing new drugs, especially in the realm of antibiotic resistance. As scientists combat microbial resistance, compounds like this may provide essential insights.
- Chirality and Selectivity: The (7S,9S) configuration indicates that chirality plays a critical role in its behavior in biological systems, often leading to variations in activity between enantiomers.
As a chemist or a student, studying such a compound enhances your appreciation for the intricacies of organic chemistry and its implications in the real world. With ongoing research, who knows what new applications might be discovered for this fascinating compound?
Synonyms
Adriblastin
ADM hydrochloride
FI 6804
4'-epi-Adriamycin hydrochloride
MLS002702107
DOX HCl
Ellence (Pharmacia)
Pidorubicin hydrochloride
ADR
Adriamycin PFS (Pharmacia)
SCHEMBL317302
CHEMBL543353
SCHEMBL29464047
Doxorubicin HCl Liposome Injection
NSC848498
CCG-208148
CCG-208196
NSC-848498
D4193
(7S,9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
5, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride
5, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-
5, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)-
L-lyxo-Hexopyranoside,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-, .alpha.-, hydrochloride
Solubility of (7S,9S)-7-(4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; hydrochloride
The solubility of (7S,9S)-7-(4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; hydrochloride is an important characteristic that influences its application and functionality in various fields.
The following factors greatly affect the solubility of this compound:
In general, compounds like this one may exhibit:
It's essential to consult empirical data or perform specific solubility tests to determine the exact solubility profile, as the solubility can vary significantly based on temperature and pH.
Understanding solubility not only assists in optimizing formulations but also in predicting the bioavailability and overall behavior of the compound in biological systems.