Skip to main content

Piribedil

ADVERTISEMENT
Identification
Molecular formula
C17H19F1N2O2
CAS number
3605-01-0
IUPAC name
8-[4-(4-fluorophenyl)-4-oxo-butyl]-2,4-dimethyl-2,8-diazaspiro[4.5]decane-1,3-dione
State
State

At room temperature, Piribedil is in a solid state.

Melting point (Celsius)
112.50
Melting point (Kelvin)
385.70
Boiling point (Celsius)
370.60
Boiling point (Kelvin)
643.80
General information
Molecular weight
317.38g/mol
Molar mass
317.3840g/mol
Density
1.2923g/cm3
Appearence

Piribedil typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility Overview

The compound 8-[4-(4-fluorophenyl)-4-oxo-butyl]-2,4-dimethyl-2,8-diazaspiro[4.5]decane-1,3-dione showcases unique solubility characteristics largely influenced by its complex molecular structure. Understanding its solubility is crucial for applications in pharmaceuticals and chemical formulations.

Key Factors Affecting Solubility

The solubility of this compound can be affected by several factors:

  • Molecular Structure: The presence of multiple functional groups can enhance solubility in polar solvents.
  • Polarity: The 4-fluorophenyl group may contribute to the overall polarity, influencing solubility in both polar and nonpolar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding with solvents can significantly affect solubility.
  • Temperature: As with many compounds, increasing the temperature may enhance solubility due to higher kinetic energy of molecules.

Solubility Insights

In summary, the solubility of 8-[4-(4-fluorophenyl)-4-oxo-butyl]-2,4-dimethyl-2,8-diazaspiro[4.5]decane-1,3-dione may exhibit:

  • Moderate Solubility: Expected in polar solvents such as ethanol and acetone.
  • Limited Solubility: May show poor solubility in nonpolar solvents like hexane.

Exploring these solubility dynamics is essential for effective use and application in various chemical environments. It is crucial to conduct experimental solubility tests to further quantify the extent of solubility under different conditions.

Interesting facts

Interesting Facts About 8-[4-(4-Fluorophenyl)-4-oxo-butyl]-2,4-dimethyl-2,8-diazaspiro[4.5]decane-1,3-dione

This intriguing compound, with a complex structure, belongs to a class of molecules known for their diverse applications in medicinal chemistry and drug development. Its unique arrangement of functional groups and spirocyclic structure contribute to its potential biological activities.

Key Characteristics:

  • Structural Diversity: The compound features a spirocyclic framework, which can play a pivotal role in the overall properties and reactivity of the molecule.
  • Fluorine Influence: The presence of a fluorine atom, specifically in the 4-fluorophenyl group, often enhances the lipophilicity and metabolic stability of the compound, making it a promising candidate for pharmaceutical applications.
  • Biological Potential: Compounds with similar structures have been investigated for their ability to modulate biological pathways, suggesting that this compound could exhibit significant pharmacological properties.

Researchers are particularly interested in the use of spiro compounds in creating novel drugs. As noted by chemists, “The unique properties offered by spirocyclic systems often lead to improved bioactivity and selectivity” which makes this compound an exciting subject for further studies.

Moreover, the compound's diazabicyclic core could lend itself to various synthetic modifications, allowing scientists to explore analogs with different pharmacological profiles. This flexibility opens the door for potential innovation in drug design aimed at treating various conditions.

In summary, the exploration of this compound could yield significant advancements in our understanding of drug mechanisms and the development of new therapeutic agents.

Synonyms
UNII-475PMO19RG
475PMO19RG
8-(4-(4-Fluorophenyl)-4-oxobutyl)-2,4-dimethyl-2,8-diazaspiro(4.5)decane-1,3-dione
3612-86-0
2,8-Diazaspiro(4.5)decane-1,3-dione, 8-(4-(4-fluorophenyl)-4-oxobutyl)-2,4-dimethyl-
Q27259016