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Parthenolide

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Identification
Molecular formula
C15H20O3
CAS number
20554-84-1
IUPAC name
8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
State
State

Parthenolide is a solid at room temperature.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
368.15
Boiling point (Kelvin)
641.30
General information
Molecular weight
248.32g/mol
Molar mass
248.3210g/mol
Density
1.2200g/cm3
Appearence

Parthenolide is a naturally occurring sesquiterpene lactone. It is a white or pale yellow crystalline solid.

Comment on solubility

Solubility of 8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one

The solubility of 8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one is an intriguing aspect of this complex organic molecule. Understanding its solubility can provide valuable insights into its potential applications and behavior in various environments. Here are some key points regarding the solubility characteristics:

  • Solvent Dependency: The solubility can significantly vary depending on the solvent used. It is essential to consider both polar and non-polar solvents when assessing its behavior.
  • Polar vs Non-Polar: Generally, compounds with complex structures may exhibit better solubility in organic solvents such as dichloromethane or acetone, while displaying limited solubility in highly polar solvents like water.
  • Temperature Influence: Temperature can play a crucial role in enhancing solubility. As temperature increases, solubility in many solvents tends to rise, allowing for better dissolution of this compound.
  • Potential Applications: Understanding solubility is vital for applications in pharmaceuticals and materials science, where this compound might be utilized. A compound with limited solubility might necessitate the development of specialized formulations.

In conclusion, the solubility profile of 8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one is complex and affected by a multitude of factors. As with many organic compounds, predicting solubility requires careful consideration of environmental contexts and specific interaction dynamics with different solvents.

Interesting facts

Interesting Facts about 8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one

This unique compound, with a complex name, showcases the intricate world of organic chemistry and the beauty of molecular structure. Here are some fascinating insights:

  • Structural Complexity: The compound exhibits a pentacyclic structure, indicating it contains five fused rings. This complexity can lead to unique physical and chemical properties.
  • Functional Groups: The presence of carbonyl (ketone) and acetyl groups contributes to the compound's reactivity and versatility in synthesis. These groups are often involved in key chemical reactions, such as nucleophilic addition.
  • Biological Relevance: Compounds with similar structures are often investigated for potential biological activities, making them interesting candidates for pharmaceuticals and natural product chemistry.
  • Synthesis Challenges: The synthesis of such complex molecules often requires multiple steps and careful control of reaction conditions to ensure the desired final product is obtained without unwanted byproducts.

In the words of famed chemist Linus Pauling: "Chemical bond is the strongest kind of bond; the covalent bond." This compound is an emblem of how covalent interactions define the behavior and properties of matter at the molecular level.

Overall, exploring compounds like 8-acetyl-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one can open doors to new scientific discoveries and enhance our understanding of organic chemistry.

Synonyms
CHEMBL4758866
NSC26104
Progesterone,17-(isopropylidenedioxy)-
16.alpha.,17-(Isopropylidenedioxy)progesterone
16.alpha.,20-dione cyclic acetal with acetone
16.alpha.,17.alpha.-Isopropylidenedioxyprogesterone
Pregn-4-ene-3, 16.alpha.,17-(isopropylidenedioxy)-
Pregn-4-ene-3, 16,17-[(1-methylethylidene)bis(oxy)], (16.alpha.)-
Pregn-4-ene-3, 16,17-[(1-methylethylidene)bis(oxy)]-, (16.alpha.)-
Pregn-4-ene-3, 16.alpha.,17-dihydroxy-, cyclic acetal with acetone